Results 111 to 120 of about 3,439,845 (290)

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Eliminative Ontic Structural Realism and the Metaphysical Underdetermination Argument: A Critique

open access: yesStudia Philosophiae Christianae
In this paper I address the problem of justifying Steven French’s eliminative ontic structural realism by the metaphysical underdetermination argument.
Damian Luty
doaj   +1 more source

From Classic Realism to Iranian Realism a Frame Work for Explaining Iranian Foreign Relations with Great Powers (1501-1979) [PDF]

open access: yesFaṣlnāmah-i Pizhūhish/hā-yi Rāhburdī-i Siyāsat, 2016
Theorizing History of Iranian foreign relations can help researchers to understand the weaknesses of Iranian foreign policy toward great powers during the last five centuries.
Seydreza Mousavinia
doaj  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

The Argument from Underconsideration and Relative Realism [PDF]

open access: yes, 2013
In this paper, through a critical examination of Wray’s version of the argument from underconsideration against scientific realism, I articulate a modest version of scientific realism.
Mizrahi, Moti
core  

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Liquid Realism: Hauntology, Lack, and Mourning as Method

open access: yesOpen Philosophy
This article proposes liquid realism as a term to describe a critical stance that constitutes a metamodern methodology. Drawing on Zygmunt Bauman’s liquid modernity, Mark Fisher’s hauntology, and Jacques Lacan’s conception of the real as structural lack,
Edgar Robert
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

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