Results 101 to 110 of about 202,206 (297)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

The reality of relations [PDF]

, 2017
Discussing the contemporary debate about the metaphysics of relations and structural realism, I analyse the philosophical significance of relational quantum mechanics (RQM).
Candiotto, Laura
core  

Predicting Great Power War in a Multipolar World: A Structural Realist Framework

Journal on Baltic Security
This article employs structural realism indicators to predict the likelihood of a great power war in today’s multipolar world. Focusing on key indicators such as changes in the balance of power, alliance systems, military expenditure, and the intensity ...
Eigil Kvernmo
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

How properties hold together in Substances [PDF]

, 2016
This article aims to clarify how aspects of current chemical understanding relate to some important contemporary problems of philosophy. The first section points out that the long-running philosophical debates concerning how properties stay together in ...
E. Earley, Joseph
core  

Helping Business Schools Engage with Real Problems: The Contribution of Critical Realism and Systems Thinking [PDF]

, 2015
The world faces major problems, not least climate change and the financial crisis, and business schools have been criticised for their failure to help address these issues and, in the case of the financial meltdown, for being causally implicated in it ...
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core   +1 more source

Neorealizm hegemoniczny jako recepta na mankamenty realizmu strukturalnego [PDF]

Przegląd Geopolityczny
Since the final decades of the last century, structural realism (neorealism) has become the dominant paradigm in the sciences of international relations as well as in geopolitics.
Marcin Adamczyk
doaj  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

On Structural Theories of International Relations: Examining Waltzian Structural Realism And Wallerstein’s World System Theory

Jurnal Hubungan Internasional, 2015
This article attempts to look at two currents of thought which both have influences on International Relations study, which is structural realism that proposed by Kenneth Waltz and ideas of the world system from Immanuel Wallerstein. In both perspectives,
Winner Agung Pribadi
doaj   +1 more source