Results 101 to 110 of about 3,620,319 (299)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Can van Fraassen's anti-realism give an account of novel predictions of unexpected phenomena? [PDF]

, 2011
In this paper it will be addressed the possibility of an account of novel predictions of unexpected phenomena by physical theories within van Fraassen's anti-realism.
Bacelar Valente, Mario
core  

Algumas notas sobre “realismo” e “ultrarealismo” em Sartre

DoisPontos, 2006
This paper intends to research the possibility of thinking the several elements of Sartre's works according to one axe named "realism". It is important to explain what "realism" means here. Not intending find out a definition of "realism". Here "realism"
Alexandre de Oliveira Torres Carrasco
doaj  

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Estudos sobre o realismo estrutural [PDF]

, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em Filosofia.Existem pelo menos duas versões do realismo estrutural, a epistemológica e a ontológica. O realismo estrutural
Steinle, William
core  

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

From National Security to International Security Copenhagen School in Crossways of Structural Realism, English School and Social Constructivism

Czech Journal of International Relations, 2004
The works Writingsof Buzan, Waever and their colleagues from COPRI represent the turning point in security analysis and in conceptualiszation of security in the first half of the 1990's.
Šárka Waisová
doaj  

REFINING STRUCTURAL REALISM: RESTORING PARSIMONY TO THE LOGIC OF AGGRESSION

KAÜ-İİBF Dergisi
Structural Realism has long struggled with two critical explanatory deficits: the puzzle of "unnecessary wars" waged by Great Powers that seemingly contradict rational security calculations, and the theory’s inability to systematically account for ...
Celil Yiğit
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Eliminative Ontic Structural Realism and the Metaphysical Underdetermination Argument: A Critique

Studia Philosophiae Christianae
In this paper I address the problem of justifying Steven French’s eliminative ontic structural realism by the metaphysical underdetermination argument.
Damian Luty
doaj   +1 more source