Results 81 to 90 of about 3,439,845 (290)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Predicting Great Power War in a Multipolar World: A Structural Realist Framework
Journal on Baltic SecurityThis article employs structural realism indicators to predict the likelihood of a great power war in today’s multipolar world. Focusing on key indicators such as changes in the balance of power, alliance systems, military expenditure, and the intensity ...
Eigil Kvernmo
doaj +1 more source
Can van Fraassen's anti-realism give an account of novel predictions of unexpected phenomena? [PDF]
, 2011 In this paper it will be addressed the possibility of an account of novel predictions of unexpected phenomena by physical theories within van Fraassen's anti-realism.
Bacelar Valente, Mario
core
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Estudos sobre o realismo estrutural [PDF]
, 2006 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em Filosofia.Existem pelo menos duas versões do realismo estrutural, a epistemológica e a ontológica. O realismo estrutural
Steinle, William
core
Scientific Realism and High-Energy Physics
, 2017 The article discusses the implications of high-energy physics for the scientific realism debate. After a brief introduction to high-energy physics, the anti-realist import of the erosion of intuition-based concepts in the context of high-energy physics ...
Dawid, Richard,, Richard Dawid
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Algumas notas sobre realismo e ultrarealismo em Sartre
DoisPontos, 2006 This paper intends to research the possibility of thinking the several elements of Sartre's works according to one axe named "realism". It is important to explain what "realism" means here. Not intending find out a definition of "realism". Here "realism"
Alexandre de Oliveira Torres Carrasco
doaj
Ontic Structural Realism [PDF]
Philosophy Compass, 2017 Abstract Ontic structural realism (OSR) is at its core the view that “structure is ontologically fundamental.” Informed from its inception by the scientific revolutions that punctuated the 20th century, its advocates often present the position as the perspective on ontology best befitting of modern physics. But the idea that structure
openaire +1 more source