Results 91 to 100 of about 202,206 (297)
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
Generalism and the Metaphysics of Ontic Structural Realism [PDF]
, 2017 Ontic structural realism (OSR) claims that all there is to the world is structure. But how can this slogan be turned into a worked-out metaphysics? Here I consider one potential answer: a metaphysical framework known as generalism (Dasgupta, 2009, 2016).
Glick, David
core +1 more source
Realism and Utopianism Revisited [PDF]
, 1998 For Carr, the contrast between utopians and realists was between ‘those who regard politics as a function of ethics and those who regard ethics as a function of politics’.
Nicholson, Michael
core +2 more sources
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Ontic structural realism and the interpretation of quantum mechanics [PDF]
, 2018 This paper argues that ontic structural realism (OSR) faces a dilemma: either it remains on the general level of realism with respect to the structure of a given theory, but then it is, like epistemic structural realism, only a partial realism; or it is ...
Esfeld, Michael
core
Critical Realism and Empirical Research Methods in Education [PDF]
, 2005 In the light of recent writings of Richard Pring, and in relation to the application of empirical research methods in education, this paper offers a corrective to a neo-realist viewpoint and develops a critical realist perspective.
Scott, David
core +3 more sources
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Ontic Structural Realism and Natural Necessity [PDF]
, 2015 J. Ladyman (1998-2009), Ladyman and Ross (2007) refine J. Worral's (1998) structural realism (SR), by developing an ontic structural realism (OSR) which they argue is a consistently naturalistic means of characterizing the ontology of fundamental physics.
Kallfelz, William
core
In Defense of Realism and Selectivism from Lyons’s Objections [PDF]
, 2019 Lyons (2016, 2017, 2018) formulates Laudan’s (1981) historical objection to scientific realism as a modus tollens. I present a better formulation of Laudan’s objection, and then argue that Lyons’s formulation is supererogatory.
Park, Seungbae
core +2 more sources