Results 71 to 80 of about 3,620,319 (299)

Quantum Entanglement Undermines Structural Realism [PDF]

open access: yes, 2022
Quantum entanglement poses a challenge to the traditional metaphysical view that an extrinsic property of an object is determined by its intrinsic properties. So structural realists might be tempted to cite quantum entanglement as evidence for structural
Park, Seungbae
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

How not to be a Realist or why we Ought to Make it Safe for Closet Structural Realists to Come out. [PDF]

open access: yes, 2010
When it comes to name-calling, structural realists have heard pretty much all of it. Among the many insults, they have been called ‘empiricist anti-realists’ but also ‘traditional scientific realists’.
Votsis, Ioannis
core  

Possible physical universes

open access: yesZagadnienia Filozoficzne w Nauce, 2005
The purpose of this paper is to discuss the various types of physical universe which could exist according to modern mathematical physics. The paper begins with an introduction that approaches the question from the viewpoint of ontic structural realism ...
Gordon McCabe
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Against digital ontology [PDF]

open access: yes, 2008
The paper argues that digital ontology (the ultimate nature of reality is digital, and the universe is a computational system equivalent to a Turing Machine) should be carefully distinguished from informational ontology (the ultimate nature of reality is
Floridi, Luciano, Floridi, L.
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Emergent Geometry in Complex Systems from Relational Dynamics: The Classical Setting

open access: yesAxioms
Geometry is typically treated as a primitive background structure within which physical processes unfold. In this work, we investigate an alternative possibility: that geometry can arise as a structural consequence of relational dynamics.
Ernesto Estrada
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Revisiting Poincaré’s conventionalism and anti-realism

open access: yesFilosofia Unisinos, 2021
Poincaré’s philosophical conception and his contribution to the Philosophy of Science has been reconsidered since the recent rise of structural realism (SR), 18 years ago.
Susana Lucero
doaj  

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