Results 21 to 30 of about 84,067 (219)

A Novel Full-Tension Crossed Cable-Truss Structure: Feasible Design and Forming Method

open access: yesBuildings
In order to avoid the instability of compression support in annular space cable truss structures, a novel full-tension crossed cable-truss structure (FCCTS) is studied.
Chenhao Xu   +4 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Damage Characteristics Analysis of High-Rise Frame-Core-Tube Building Structures in Soft Soil Under Earthquake Action

open access: yesBuildings
This paper analyzes the seismic performance and damage characteristics of high-rise frame-core-tube structures on soft soil, explicitly incorporating dynamic soil–pile–structure interaction (SSI).
Jiali Liang   +6 more
doaj   +1 more source

Preliminary Research on Reinforcement Schemes for New Composite Dam Structure of Mortar Masonry-Concrete ——A Case Study of Chi'ao Reservoir in Shenzhen City

open access: yesRenmin Zhujiang, 2022
The main masonry dam of Chi'ao Reservoir in Shenzhen faces insufficient overall anti-sliding stability safety margin and leakage of the left dam abutment.In view of these problems,this paper proposed a new reinforcement technology for a composite dam of ...
CHEN Yu   +3 more
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Challenges and solutions in reinforcing self-built homes: experiences from Villa Maria del Triunfo, Lima, Peru

open access: yesFrontiers in Built Environment
This study assesses H-shaped steel profiles (W8×31) as a retrofit solution for self-built dwellings in the Human Settlement (AA.HH). Ciudad de Gosen, Villa María del Triunfo (Lima, Peru). A four-part workflow was applied: i.
Emilio J. Medrano‐Sánchez   +1 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Parametric CFD-FEA Study on the Aerodynamic and Structural Performance of NaviScreen for Wind Resistance Reduction in Medium-Sized Commercial Ships

open access: yesJournal of Marine Science and Engineering
Meeting the International Maritime Organization’s (IMO) 2050 targets for reducing greenhouse gas (GHG) emissions requires cost-effective solutions that minimize wind resistance without compromising safety, particularly for medium-sized multipurpose ...
Jin-Man Kim   +3 more
doaj   +1 more source

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