Results 111 to 120 of about 1,329,617 (295)

Detecting structural similarity of ligand interactions in the lipid metabolic system including enzymes, lipid-binding proteins and nuclear receptors [PDF]

, 2011
Clara Shionyu‐Mitsuyama, Tomonori Waku, Takuma Shiraki, Takuji Oyama, Tsuyoshi Shirai, Kosuke Morikawa   +5 more
openalex   +1 more source

Structural-Semantic Features of Composite Idiom and Phraseological Unit: Similarities and Differences [PDF]

, 2020
Nataliya Mikhailovna Merkur'eva
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Structural modeling of the flagellum MS ring protein FliF reveals similarities to the type III secretion system and sporulation complex [PDF]

, 2015
Julien R. C. Bergeron
openalex   +1 more source

Language classification from bilingual word embedding graphs

, 2016
We study the role of the second language in bilingual word embeddings in monolingual semantic evaluation tasks. We find strongly and weakly positive correlations between down-stream task performance and second language similarity to the target language ...
Eger, Steffen, Hoenen, Armin, Mehler, Alexander   +2 more
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Autoencoder-Based Unsupervised Surface Defect Detection Using Two-Stage Training

Journal of Imaging
Accurately detecting defects while reconstructing a high-quality normal background in surface defect detection using unsupervised methods remains a significant challenge.
Tesfaye Getachew Shiferaw, Li Yao
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Identification of new superwarfarin-type rodenticides by structural similarity. The docking of ligands on the vitamin K epoxide reductase enzyme’s active site

Acta Universitatis Sapientiae: Agriculture and Environment, 2015
The rodenticide brodifacoum is highly toxic to mammals and birds, and extremely toxic to fish. It is a highly cumulative poison due to its high lipophilicity and extremely slow elimination. For this reason, it may be interesting to find similar compounds
Ferencz László, Muntean Daniela Lucia
doaj   +1 more source

Crystal structure of glutathione synthetase at optimal pH: domain architecture and structural similarity with other proteins [PDF]

, 1996
K. Matsuda, Kenji Mizuguchi, Takaaki Nishi­oka, Hiroaki Kato, Nobuhiro Gō, Jun’ichi Oda   +5 more
openalex   +1 more source