Results 71 to 80 of about 4,318,402 (294)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Empirical measurements of lexical similarity in noun phrase conjuncts [PDF]
, 2007 The ability to detect similarity in conjunct heads is potentially a useful tool in helping to disambiguate coordination structures - a difficult task for parsers. We propose a distributional measure of similarity designed for such a task.
Hogan, Deirdre
core +3 more sources
ISPRS International Journal of Geo-Information, 2018 Existing spatial community detection algorithms are usually modularity based. Motivated by different applications, these algorithms build appropriate spatial null models to describe spatial effects on the connection of nodes.
You Wan, Yaolin Liu
doaj +1 more source
Structural aspects of visual similarity [PDF]
Memory & Cognition, 1978 The hypothesis that visual representations for lines and/or points are independent structural units was tested using similarity judgment and speeded discrimination for pairs of six-segment letter-like figures. The stimuli were constructed such that each of two comparison figures had five segments in common with a standard figure. One figure was similar
openaire +2 more sources
MaGSoundDST-3D automatic inversion of magnetic and gravity data based on the differential similarity transform [PDF]
, 2010 We present an automatic procedure - Magnetic And Gravity SOUNDing Differential Similarity Transform (MaGSoundDST) - for inversion of regular or irregular magnetic- and gravity-grid data measured on even or uneven surfaces.
Arauzo-Bravo, Marcos J. +3 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Iterative Phase-Only Hologram Generation Based on the Perceived Image Quality
Applied Sciences, 2019 Image quality metrics are a critical element in the iterative Fourier transform algorithms (IFTAs) for the computer generation of phase-only holograms.
Haining Yang, Daping Chu
doaj +1 more source
Acetylcholinesterases – the structural similarities and differences
Journal of Enzyme Inhibition and Medicinal Chemistry, 2007 Acetylcholinesterase (AChE) is a widely spread enzyme playing a very important role in nerve signal transmission. As AChE controls key processes, its inhibition leads to the very fast death of an organism, including humans. However, when this feature is to be used for killing of unwanted organisms (i.e. mosquitoes), one is faced with the question - how
Jirí, Wiesner +4 more
openaire +2 more sources
On calculating structural similarity metrics in population-based structural health monitoring [PDF]
The newly introduced discipline of Population-Based Structural Health Monitoring (PBSHM) has been developed in order to circumvent the issue of data scarcity in “classical” SHM.
Brennan, D.S. +3 more
core +1 more source