Results 81 to 90 of about 510,563 (307)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Change Detection Based on Multi-Feature Clustering Using Differential Evolution for Landsat Imagery

open access: yesRemote Sensing, 2018
Change detection (CD) of natural land cover is important for environmental protection and to maintain an ecological balance. The Landsat series of satellites provide continuous observation of the Earth’s surface and is sensitive to reflection of ...
Mi Song, Yanfei Zhong, Ailong Ma
doaj   +1 more source

Similarity Search in Structured Data [PDF]

open access: yes, 2003
Recently, structured data is getting more and more important in database applications, such as molecular biology, image retrieval or XML document retrieval. Attributed graphs are a natural model for the structured data in those applications. For the clustering and classification of such structured data, a similarity measure for attributed graphs is ...
Hans-Peter Kriegel, Stefan Schönauer
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Similarity consideration of structural bifurcation buckling

open access: yes, 1999
Many structural bifurcation buckling problems exhibit a scaling or power law property. Dimensional analysis is used to analyze the general scaling property.
赵亚溥   +1 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Drivers of structural similarity

open access: yes, 2018
The dataset contains a measure of structural similarity/convergence (pairwise Krugman specialization index) along with 54 potential determinants of structural ...
Beck, K (via Mendeley Data)
core   +1 more source

Road Extraction by Using Atrous Spatial Pyramid Pooling Integrated Encoder-Decoder Network and Structural Similarity Loss

open access: yesRemote Sensing, 2019
The technology used for road extraction from remote sensing images plays an important role in urban planning, traffic management, navigation, and other geographic applications.
Hao He   +4 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Structure Learning with Similarity Preserving

open access: yesCoRR, 2019
Leveraging on the underlying low-dimensional structure of data, low-rank and sparse modeling approaches have achieved great success in a wide range of applications. However, in many applications the data can display structures beyond simply being low-rank or sparse.
Zhao Kang 0001   +4 more
openaire   +2 more sources

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