Results 81 to 90 of about 4,318,402 (294)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Change Detection Based on Multi-Feature Clustering Using Differential Evolution for Landsat Imagery

open access: yesRemote Sensing, 2018
Change detection (CD) of natural land cover is important for environmental protection and to maintain an ecological balance. The Landsat series of satellites provide continuous observation of the Earth’s surface and is sensitive to reflection of ...
Mi Song, Yanfei Zhong, Ailong Ma
doaj   +1 more source

Local similarity in RNA secondary structures [PDF]

open access: yesComputational Systems Bioinformatics. CSB2003. Proceedings of the 2003 IEEE Bioinformatics Conference. CSB2003, 2004
We present a systematic treatment of alignment distance and local similarity algorithms on trees and forests. We build upon the tree alignment algorithm for ordered trees given by Jiang et. al (1995) and extend it to calculate local forest alignments, which is essential for finding local similar regions in RNA secondary structures.
Höchsmann, Matthias   +3 more
openaire   +4 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Road Extraction by Using Atrous Spatial Pyramid Pooling Integrated Encoder-Decoder Network and Structural Similarity Loss

open access: yesRemote Sensing, 2019
The technology used for road extraction from remote sensing images plays an important role in urban planning, traffic management, navigation, and other geographic applications.
Hao He   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Structure Learning with Similarity Preserving

open access: yesCoRR, 2019
Leveraging on the underlying low-dimensional structure of data, low-rank and sparse modeling approaches have achieved great success in a wide range of applications. However, in many applications the data can display structures beyond simply being low-rank or sparse.
Zhao Kang 0001   +4 more
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Dynamic Structural Similarity on Graphs

open access: yesCoRR, 2018
8 pages, 7 figures, 1 table, Submitted for peer-review to the conference ASONAM ...
Eduar Castrillo   +2 more
openaire   +2 more sources

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