Results 71 to 80 of about 1,028,024 (317)

Principles of complex multi-stage processes decomposition into component subsystems [PDF]

E3S Web of Conferences
The article deals with the decomposition of complex multi-stage processes into components and interconnected by material and information flows. Decomposition is carried out to create micro-models for each subsystem.
Sharifzhanova Nilufar
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Idealisation error control for aerospace virtual structural testing [PDF]

, 2009
This thesis addresses idealisation error control for the nonlinear finite element method. The focus is on accurate failure prediction of mid-size aerospace structures.
Hetey, Laszlo
core  

Consideration of plasticity within the design of timber structures due to connection ductility [PDF]

, 2011
The plastic behavior of fasteners in timber structures has gained more and more interest within recent years. In particular, dowel type fasteners show a significant ductile behavior if a certain embedded length of the dowel is ensured.
Jorissen, AJM André, Jorissen, A.J.M., Kuhlmann, U, Kuhlmann, U., Brühl, F, Brühl, F., Ulrike Kuhlmann, André Jorissen, Frank Brühl   +8 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Study of optimisation strategies for aircraft structural design [PDF]

, 2012
Optimisation plays an important role in structural design. Structural design optimisation is not only a matter of weight reduction of the structure; it can be used to optimise any type of objectives.
Huang, Feng
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

An integrated structural health monitoring approach to composite-based pipeline repair [PDF]

, 2011
One of the most common problems in the structural integrity of industrial pipelines is external corrosion. Composite materials have been accepted as a repair option to restore the original strength of the effected damaged section but the approach to ...
Abd Murad, Mahadi
core  

Prefabricated lightweight construction with post-tensioning: A conceptual design prototype of 3D-printed polymer slab system

Frontiers of Architectural Research
The confluence of structural optimization and additive manufacturing (AM) has significantly expanded the design space of architectural tectonics. This research explores the integration of architectural tectonics and rationalization in prefabricated ...
Yizhuo Liu, Yuan Zhang, Hao Hua
doaj   +1 more source