Results 131 to 140 of about 1,047,704 (361)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Structural basis for the removal and exclusion of uracil from DNA [PDF]

open access: bronze, 1996
C.D. Mol   +5 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Evaluating power in development programmes [PDF]

open access: yes, 2007
SINCE the mid-1990s, there has been a growing interest in, and use of discourse theories within development studies to understand contexts of power inequalities between individuals, groups and institutions.
Simon-Kumar, Rachel
core  

Archaeological possibilities for feminist theories of transition and transformation

open access: yes, 2008
Archaeology takes up material fragments from distant andrecent pasts to create narratives of personal and collective identity. It is, therefore, a powerful voice shaping our current and future social worlds.
Marshall, Yvonne
core   +1 more source

Emmanuel Lévinas and structuralism

open access: yesVeritas, 2006
O estruturalismo alcançou seu zênite de influência no pensamento francês nos anos 60 e 70 do séc. XX, quando Lévinas escreveu os seus livros mais importantes.
Levy, Ze'ev
doaj  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Univalent Foundations as a Foundation for Mathematical Practice [PDF]

open access: yes, 2018
I prove that invoking the univalence axiom is equivalent to arguing 'without loss of generality' (WLOG) within Propositional Univalent Foundations (PropUF), the fragment of Univalent Foundations (UF) in which all homotopy types are mere propositions.
Crane, Harry
core   +1 more source

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