Results 81 to 90 of about 1,988,984 (222)
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Study on the relationship between structure and properties of electro-hydraulic positioning actuators [PDF]
Archive of Mechanical EngineeringIn this work, a novel perspective is proposed to develop schematics solutions for electro-hydraulic positioning actuators. The basis of the design approach has been established, which includes: a set of possible desired properties of actuators; a series ...
Qiang Li, Oleksandr Uzunov
doaj +1 more source
Demographic Structure and the Security of Property Rights in Developing Countries – An Empirical Exploration [PDF]
It is often argued that countries with a high population share of children and young workers should attract large capital inflows from aging industrialized economies.
Philipp an de Meulen, Philipp Harms
core
Band gap prediction for large organic crystal structures with machine learning
, 2019 Machine-learning models are capable of capturing the structure-property relationship from a dataset of computationally demanding ab initio calculations.
Balatsky, Alexander V. +3 more
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
ECONOMIC ANALYSIS AND EFFICIENCY IN PUBLIC EXPENDITURE [PDF]
Benefit-Cost Analysis involves several steps: development of a program information structure (product categories), estimating the production function, pricing benefits and costs, adjusting for opportunity costs, choice of investment criteria, and ...
Schmid, A. Allan
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Applications in Energy and Combustion ScienceThe ever-increasing importance of both energy security and sustainability motivates the design of carbon-neutral petroleum replacements from renewable resources. Fuel candidates are conventionally selected from existing databases with limited scope. This
Zhuo Chen +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source