Results 91 to 100 of about 675,511 (236)

Study on the relationship between structure and properties of electro-hydraulic positioning actuators [PDF]

Archive of Mechanical Engineering
In this work, a novel perspective is proposed to develop schematics solutions for electro-hydraulic positioning actuators. The basis of the design approach has been established, which includes: a set of possible desired properties of actuators; a series ...
Qiang Li, Oleksandr Uzunov
doaj   +1 more source

Innovation and Intellectual Property Rights [PDF]

Very little empirical evidence exists on the relationship between intellectual property rights and innovation. Existing studies tend to be indirect and do not consider the influence of IPRs on innovation per se; nor do they adequately allow for the ...
Sunil Kanwar
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Children's Interests in Division of Property on Relationship Breakdown [PDF]

, 2019
The breakdown of a marriage, civil union, or de facto relationship inevitably affects children of the relationship. The question this paper addresses is whether the interests of children should be taken into account in the division of property between ...
Henaghan, M, Peart, Nicola
core   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Descriptors-based machine-learning prediction of cetane number using quantitative structure–property relationship

Energy and AI
The physicochemical properties of liquid alternative fuels are important but difficult to measure/predict, especially when complex surrogate fuels are concerned.
Rodolfo S.M. Freitas, Xi Jiang
doaj   +1 more source

Structure–Photophysical Property Relationship of Conjugated Rod–Coil Block Copolymers in Solutions [PDF]

, 2016
Structure–Photophysical Property Relationship of Conjugated Rod–Coil Block Copolymers in ...
Heng-Kwong Tsao (1468258), Yung-Lung Lin (2109823), Jui-Hsiang Hung (313316), Yu-Jane Sheng (1449079)   +3 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Local Structure-Property Relationship in Some Selected Solid State Materials [PDF]

, 2015
The thesis entitled “Local structure-property relationship in some selected Solid State Materials” mainly focuses on two fundamental topics: (a) evaluation of some standard global structural concepts in terms of local structure to provide a unique ...
Mukherjee, Soham
core