Results 111 to 120 of about 9,692,539 (313)
Scientific ReportsWeight-bearing computed tomography (WBCT) has set a new standard for assessing foot alignment under physiological loading conditions. However, few studies have systematically quantified morphological differences between weight-bearing (WB) and non-weight-
Jing Li +8 more
doaj +1 more source
Bone & Joint OpenAims: Weightbearing CT (WBCT) has set a new standard for the assessment of foot and ankle alignment in patients with progressive collapsing foot deformity (PCFD) under physiological loading conditions compared with conventional CT.
Jing Li +8 more
doaj +1 more source
, 2019 ACPFLI-STRUCTURE-2Optimized geometries of intermediates A-D and transition states TS1-3 starting from structure 2 taken from MD trajectory of acetylated (AcPFL I) topology without CoA in the active site.
Marko Hanzevacki (5094041)
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 2019 ACPFLII-STRUCTURE-1Optimized geometries of intermediates A-D and transition states TS1-3 starting from structure 1 taken from MD trajectory of acetylated (AcPFL II) topology without CoA in the active site.
Marko Hanzevacki (5094041)
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Original scientific paper Benzenoid isomers with greatest and smallest Kekulé [PDF]
, 2005 : In families of benzenoid isomers, the species with the greatest and smallest value of the Kekulé structure count (K) possess, respectively, the greatest and smallest thermodynamic stability and, respectively, the smallest and greates reactivity.
Structure Counts
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Monolithic optoelectronic circuit design for on-chip terahertz applications
APL PhotonicsWe demonstrate a monolithic coplanar stripline platform for on-chip terahertz (THz) generation, transmission, and detection, addressing key challenges of mode purity, bandwidth, and referencing. Capacitive coupling of the photoconductive generator switch
Kateryna Kusyak +8 more
doaj +1 more source