Results 101 to 110 of about 9,663,658 (313)

Social Structure of Poland, 1988

open access: yes
The primary objective of the study is the overall characteristics of the social structure of Polish society of the second half of the 80's. Topics include: Class divisions, the problem inter-class distances, the issue of physical and psychological burden
Mach, Bogdan W.   +8 more
core   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Defect structure in nanomaterials /

open access: yes, 2012
Nanomaterials exhibit unique mechanical and physical properties compared to their coarse-grained counterparts, and are consequently a major focus of current scientific research.
Gubicza, Jeno,author.
core  

Crystal structure of recombinant human interleukin-22

open access: yes, 2015
Interleukin-22 (IL-10-related T cell-derived inducible factor/IL-TIF/IL-22) is a novel cytokine belonging to the IL-10 family. Recombinant human IL-22 (hIL-22) was found to activate the signal transducers and activators of transcription factors I and 3 ...
Colau, D   +5 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Structure and functions of Candida rugosa lipase

open access: yes, 2014
[[sponsorship]]植物暨微生物學研究所[[note]]已出版;有審查制度 ...
J. F. Shaw, Shaw, J. F.
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

THE STRUCTURE AND ORGANIZATION OF A POETIC CREATIVE ENTITY

open access: yes, 2014
In the report the author discloses the meaning of the role of the structure and organization of creative work in terms of the systems approach. Integration of mental, verbal and textual hypostases of the text as a complex system is studied by the ...
Suvorova, Т.
core  

Trimerization of 1,2‐Diaminocyclohexane Catalyzed by a Metal–Organic Cage Tandem Catalyst with Dual Biomimetic Active Sites

open access: yesAdvanced Science
Cascade reactions that form multiple chemical bonds in one synthetic step are important for the synthesis of complex molecules. Molecular catalysts for cascade reactions generally require two or more catalytic centers, yet anchoring distinct catalytic ...
Xiao‐Jun Chai   +10 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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