Results 81 to 90 of about 11,764,588 (312)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Discover Applied SciencesRecycled fine aggregates (RFA), as a recyclable and reusable material, can help reduce the exploitation of natural resources and promote resource recycling.
Yanfen Gong +12 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Scientific ReportsA share-point is a cutting edge of the ploughshare, the crucial component of a horizontally reversible plough (HRP). Our previous trials in sandy loam soil indicated that severe abrasion/attrition wear with white materials appeared at the share-point ...
Yan-Chen Li +6 more
doaj +1 more source
Molecules, 2018 Eukaryotic transcription initiation is mediated by interactions between transcriptional activators and the mediator coactivator complex. Molecular interaction of p53 transcription factor with mediator complex subunit 25 (MED25) is essential for its ...
Min-Sung Lee +3 more
doaj +1 more source
RUNNING HEAD: Visual Structure CORRESPONDENCE:
, 2008 1 A functional characterization of structure processing A computational-level analysis of the processes dealing with object and scene structure requires that we first identify the common functional characteristics of structure-related behavioral tasks ...
Shimon Edelman +2 more
core
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Structural determination of small proteins by cryo-EM using a coiled coil module strategy
Scientific ReportsElectron cryo-microscopy (Cryo-EM) has traditionally been used for structural determination of proteins larger than 50 kDa. Recently, various approaches, such as fusion to a scaffold or the use of DARPins-cages, have been developed to extend its ...
Samson Camille +5 more
doaj +1 more source
Crystal structure of recombinant human interleukin-22
, 2015 Interleukin-22 (IL-10-related T cell-derived inducible factor/IL-TIF/IL-22) is a novel cytokine belonging to the IL-10 family. Recombinant human IL-22 (hIL-22) was found to activate the signal transducers and activators of transcription factors I and 3 ...
Colau, D +5 more
core +1 more source