Results 71 to 80 of about 11,764,588 (312)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structure-based sequence comparison versus structure comparison.

, 2019
Structure-based sequence comparison versus structure comparison.
Philipp Hornburg (1998727), Emma-Ruoqi Xu (8157129), Florian Sauer (636932), Simone Mueller (8157123), Deniz Ugurlar (8157126), Matthias Wilmanns (170797), Spyros D. Chatziefthimiou (183835)   +6 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

STRUCTURAL INTEGRITY OF MATERIALS AND STRUCTURES

Engineering Structures and Technologies, 2017
"Editorial.
Correia, José, De Jesus, Abílio, Calçada, Rui   +2 more
openaire   +3 more sources

Structure of Zirconia

, 2010
Rotation of the structure of zirconia.
DoITPoMS, University of Cambridge
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Engineering Active Metal and Nonmetal Sites in Porous Structures of Metal‐Hydroxide Clusters for Enhanced D2/H2 Uptake and Separation

Advanced Science
Efficient deuterium separation from hydrogen isotopic mixtures poses a significant challenge due to the nearly identical physicochemical properties of D2 and H2.
Zhuozhou Xie, Zhu Zhuo, Zi‐Ang Nan, Qing Li, Wenlin Wu, Yunzhe Zhou, Zi‐Xiu Lu, Jin Liu, Luyao Liu, Wenjing Wang, Daqiang Yuan, You‐Gui Huang   +11 more
doaj   +1 more source

FINANCIAL STRUCTURE AND INDUSTRIAL STRUCTURE

, 2010
This paper explores the relationship between financial structure and industrial structure in a panel cointegration framework, using annual data for 29 countries and 28 industrial sectors for the period 1990–2001.
Apergis, Nicholas, Antzoulatos, Angelos, Tsoumas, Chris   +2 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Flexural behavior of RC beams strengthened with CFRP sheets and ECC layers

Discover Applied Sciences
To further enhance the flexural capacity and ductility of reinforced concrete (RC) beams, this study proposes an innovative strengthening method. This approach, referred to as Carbon Fiber Reinforced Polymer (CFRP) and Engineered Cementitious Composite ...
Xiaobing Hou, Ziyi Song, Han Song, Xingyao Wang, Junhua Guo, Songqiang Wan, Jingli Yang, Hongbo Xiao, Yanfen Gong, Long Liu   +9 more
doaj   +1 more source