Results 21 to 30 of about 8,160,938 (248)

Benchmark of tools for in silico prediction of MHC class I and class II genotypes from NGS data

BMC Genomics, 2023
Background The Human Leukocyte Antigen (HLA) genes are a group of highly polymorphic genes that are located in the Major Histocompatibility Complex (MHC) region on chromosome 6. The HLA genotype affects the presentability of tumour antigens to the immune
Arne Claeys, Peter Merseburger, Jasper Staut, Kathleen Marchal, Jimmy Van den Eynden   +4 more
doaj   +1 more source

Interconvertible vanadium-seamed hexameric pyrogallol[4]arene nanocapsules

Nature Communications, 2018
Adapting the cavity of a coordination capsule generally involves the addition or removal of subcomponents. Here, the authors report two vanadium-organic coordination nanocapsules with the same number of components but variable cavity sizes—an expanded ...
Kongzhao Su, Mingyan Wu, Daqiang Yuan, Maochun Hong   +3 more
doaj   +1 more source

Experimental Research on Damping Effect of Double-Layer Tuned Mass Damper for High-Rise Structure

Shock and Vibration, 2021
A double-layer tuned mass damper (DTMD) has advantages of wide damping frequency band and strong robustness. At present, there is a lack of seismic design methods for high-rise structures based on DTMDs.
Botan Shen, Jin Wang, Weibing Xu, Yanjiang Chen, Weiming Yan, Jianhui Huang, Zhenyun Tang   +6 more
doaj   +1 more source

Moving in the Dark: Enlightening the Spatial Population Ecology of European Cave Salamanders

Population Ecology, EarlyView.
We assessed individual interactions, movement ecology and activity patterns of a subterranean population of Speleomantes strinatii, applying spatial capture–recapture modeling to a photographic dataset of 104 individuals. ABSTRACT Space use and movement are fundamental aspects of organisms' ecology, mirroring individual fitness, behavior, and life ...
Giacomo Rosa, Andrea Costa, Sebastiano Salvidio   +2 more
wiley   +1 more source

Thrombospondin-1 Silencing Ameliorates Osteoblastic Differentiation of Aortic Valve Interstitial Cells via Inhibiting Nuclear Factor-κB Pathway

Cardiovascular Therapeutics
Conclusions: The present study has shown that TSP-1 silencing could mitigate the development of CAVD by inhibiting NF-κB-mediated inflammation. We propose that targeting TSP-1-mediated NF-κB pathway could provide a potential therapeutic method for ...
Qing Li, Chengxiang Song, Zisong Wei, Junli Li, Hao Zhou, Shuoding Wang, Hongde Li, Haoran Yang, Qiang Luo, Mao Chen   +9 more
doaj   +1 more source

On how the mechanochemical and co-precipitation synthesis method changes the sensitivity and operating range of the Ba2Mg1-xEuxWO6 optical thermometer

Scientific Reports, 2021
The suitability of Ba2MgWO6 (BMW) double perovskite doped with Eu3+ for the construction of an optical thermometer was tested. It has been shown that by controlling the conditions of BMW synthesis, the sensitivity of the optical thermometer and the ...
Quan T. H. Vu, Bartosz Bondzior, Dagmara Stefańska, Natalia Miniajluk-Gaweł, Maciej J. Winiarski, Przemysław J. Dereń   +5 more
doaj   +1 more source

An Adaptive Management Model for Brown Bears in Hokkaido: Based on Total Population and the Number of Nuisance Bears

Population Ecology, EarlyView.
Bear management changes management actions according to the horizontal axis of the population size and the vertical axis of the number of nuisance bears. Aiming for the target population size of Ntar, Actions I and II protect the bears, and Action IV reduces the population.
Hiroyuki Matsuda, Akira Maki, Tsutomu Mano, Hifumi Tsuruga, Hino Takafumi, Shinichi Horino   +5 more
wiley   +1 more source

A clinically annotated post-mortem approach to study multi-organ somatic mutational clonality in normal tissues

Scientific Reports, 2022
Recent research on normal human tissues identified omnipresent clones of cells, driven by somatic mutations known to be responsible for carcinogenesis (e.g., in TP53 or NOTCH1). These new insights are fundamentally changing current tumor evolution models,
Tom Luijts, Kerryn Elliott, Joachim Tetteh Siaw, Joris Van de Velde, Elien Beyls, Arne Claeys, Tim Lammens, Erik Larsson, Wouter Willaert, Anne Vral, Jimmy Van den Eynden   +10 more
doaj   +1 more source

Stereolithography additive manufacturing and sintering approaches of SiC ceramics

Open Ceramics, 2021
Stereolithography additive manufacturing (SL-AM) has been reported to produce SiC ceramic recently. However, both the density and strength of the stereolithography additive manufactured SiC ceramic need to be improved.
Xuejian Bai, Guojiao Ding, Keqiang Zhang, Wenqing Wang, Niping Zhou, Daining Fang, Rujie He   +6 more
doaj   +1 more source

Speciation Through the Lens of Population Dynamics: A Theoretical Primer on How Small and Large Populations Diverge

Population Ecology, EarlyView.
Population size and dynamics fundamentally shape speciation by influencing genetic drift, founder events, and adaptive potential. Small populations may speciate rapidly due to stronger drift, whereas large populations harbor more genetic diversity, which can alter divergence trajectories. We highlight theoretical models that incorporate population size
Ryo Yamaguchi, Hidaka Kubo, Tokuya Ogawa, Hayate Omura   +3 more
wiley   +1 more source