Results 121 to 130 of about 5,072,023 (302)

Baryon number violating hydrogen decay

Physics Letters B
Most studies on baryon number violating (BNV) processes in the literature focus on free or bound nucleons in nuclei, with limited attention given to the decay of bound atoms.
Wei-Qi Fan, Yi Liao, Xiao-Dong Ma, Hao-Lin Wang   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Deep learning for predicting the evolution of chiral active particles motion based on experimental platform

New Journal of Physics
Chiral active particles (CAPs) exhibit intricate collective behaviors, yet their characterization via traditional simulations or experiments is often labor-intensive and resource-demanding.
Xiaoyuan Yu, Renjie Wang, Baoquan Ai, Fengguo Li   +3 more
doaj   +1 more source

The nucleon properties in finite temperature and density with Gaussian fluctuations

Physics Letters B
We investigate the properties of nucleons at finite temperature and density using a two-flavor quark meson model with Gaussian fluctuations that extend beyond the mean-field approximation.
Peixin Weng, Bingtao Li, Yiming Lyu, Song Shu, Hui Zhang   +4 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Collective motion of pulsating active particles in confined structures

New Journal of Physics
The collective motion of pulsating active particles with periodic size contraction is investigated in a two-dimensional asymmetric channel. Our findings reveal that changes in particle size can act as a non-equilibrium driving force, disrupting the ...
Wan-hua Liu, Wei-jing Zhu, Bao-quan Ai
doaj   +1 more source

Flavor dependence of jet quenching in heavy-ion collisions from a Bayesian analysis

Physics Letters B
We investigate the flavor dependence of jet quenching, by performing a systematic analysis of medium modifications on the inclusive jet, γ+jet, and b-jet in Pb+Pb collisions at the LHC.
Shan-Liang Zhang, Enke Wang, Hongxi Xing, Ben-Wei Zhang   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

AI-assisted quantitative deciphering of molecular configuration and steric effects for high-performance zinc battery electrolytes

Communications Materials
Zinc-ion batteries depend on molecular design of electrolyte additives for performance optimization. However, the influence of molecular structure and steric effects on solvation behavior has not been systematically quantified.
Yizhan Gao, Rongkun Sun, Yiqian Shi, Zhigang Shao   +3 more
doaj   +1 more source