Results 201 to 210 of about 5,072,023 (302)

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Analysis of the structure and interactions of the SARS-CoV-2 ORF7b accessory protein. [PDF]

Proc Natl Acad Sci U S A
Nguyen MH, Palfy G, Fogeron ML, Ninot Pedrosa M, Zehnder J, Rimal V, Callon M, Lecoq L, Barnes A, Meier BH, Böckmann A.   +10 more
europepmc   +1 more source

Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha. [PDF]

mBio, 2021
Liu J, Vanarsdall A, Chen DH, Chin A, Johnson D, Jardetzky TS.   +5 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Vibration Serviceability Assessment of Floor Structures: Simulation of Human-Structure-Environment Interactions Using Agent-Based Modeling. [PDF]

Sensors (Basel)
Shahabpoor E, Berari B, Pavic A.
europepmc   +1 more source

Autosomal Recessive Cutis Laxa 1C Mutations Disrupt the Structure and Interactions of Latent TGFβ Binding Protein-4. [PDF]

Front Genet, 2021
Alanazi YF, Lockhart-Cairns MP, Cain SA, Jowitt TA, Weiss AS, Baldock C.   +5 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Structure and interactions of the endogenous human Commander complex. [PDF]

Nat Struct Mol Biol
Laulumaa S, Kumpula EP, Huiskonen JT, Varjosalo M.   +3 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Wild Ungulate Prey Size and Feeding Group Demographic Structure Affect Interactions and Per Capita Food Intake of African Pride Lions in East African Maasai Steppe. [PDF]

Ecol Evol
Tomeka TO, Kissui BM, Ukio IG, Mushi FR, Mremi RF, Roberts NJ, Holyoak M, Jiang G.   +7 more
europepmc   +1 more source