Results 31 to 40 of about 2,034,226 (308)

Structural and functional analyses of PAS domain interactions of the clock proteins Drosophila PERIOD and mouse PERIOD2 [PDF]

, 2009
PERIOD proteins are central components of the Drosophila and mammalian circadian clocks. The crystal structure of a Drosophila PERIOD (dPER) fragment comprising two PER-ARNT-SIM (PAS) domains (PAS-A and PAS-B) and two additional C-terminal alpha-helices (
Strauss, Holger M, Wolf, Eva, Schulze, Sabrina, Sven Hennig, Arens, J., Hennig, Sven; id_orcid, Yildiz, O., Strauss, Holger M., Holger M Strauss, Julia Arens, Kramer, Achim, Arens, Julia, Sabrina Schulze, Schulze, S., Eva Wolf, Vanselow, Katja, Yildiz, Özkan, Katja Vanselow, Strauss, H., Hennig, S., Kramer, A., Vanselow, K., Wolf, E., Strauss, H. M., Achim Kramer, Ozkan Yildiz, Hennig, Sven   +26 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A systematic investigation on dark matter-electron scattering in effective field theories

Journal of High Energy Physics
In this paper, we systematically investigate the general dark matter-electron interactions within the framework of effective field theories (EFTs). We consider both the non-relativistic (NR) EFT and the relativistic EFT descriptions of the interactions ...
Jin-Han Liang, Yi Liao, Xiao-Dong Ma, Hao-Lin Wang   +3 more
doaj   +1 more source

EPLC-Pose: A Lightweight Student Posture Recognition Network Under Panoramic Classroom

IEEE Access
With the development of intelligence, concepts such as “smart classroom” have emerged, and the intelligent recognition of classroom behavior has become a hot research topic. However, the current intelligent recognition of classroom behavior
Yanhong Ji, Yibo Jin, Zuxuan Wang, Suyan Tan   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Probing dimension-8 SMEFT operators through neutral meson mixing

Journal of High Energy Physics
We investigate the impact of effective interactions of dimension-8 (dim-8) operators in the standard model effective field theory (SMEFT) on neutral meson mixing, focusing on the K 0 − K ¯ 0 $$ {K}^0-{\overline{K}}^0 $$ , B d , s − B ¯ d , s $$ {B}_{d,s}-
Yi Liao, Xiao-Dong Ma, Hao-Lin Wang
doaj   +1 more source

Soil–Water–Structure Interactions

Geotechnics, 2023
Interactions between soil, fluids (e.g., water), and structures are intrinsic to most geotechnical problems. However, these can be extremely complex and further understanding is needed in this field. Soil–water–structure interactions can be studied on many different scales (micro to macro) and perspectives (experimental, numerical, and theoretical). In
Alba Yerro, Francesca Ceccato
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control

Nature Communications, 2021
In Saccharomyces cerevisiae, unchecked proliferation of Ty1 retrotransposons is controlled by the process of copy number control (CNC), which requires the p22/p18 protein, translated from an internal transcript within the Ty1 GAG gene.
Matthew A. Cottee, Sean L. Beckwith, Suzanne C. Letham, Sarah J. Kim, George R. Young, Jonathan P. Stoye, David J. Garfinkel, Ian A. Taylor   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source