Results 81 to 90 of about 1,492,998 (305)

ON THE GAUGE STRUCTURE OF THE CALCULUS OF VARIATIONS WITH CONSTRAINTS [PDF]

open access: yesInternational Journal of Geometric Methods in Modern Physics, 2011
A gauge-invariant formulation of constrained variational calculus, based on the introduction of the bundle of affine scalars over the configuration manifold, is presented. In the resulting setup, the "Lagrangian" ℒ is replaced by a section of a suitable principal fiber bundle over the velocity space.
D. Bruno, G. Luria, Pagani, Enrico
openaire   +3 more sources

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

When synchrony meets diachrony : The negation system of Fɛʔfɛʔ in the light of the Jespersen Cycle [PDF]

open access: yes, 2015
This dissertation is concerned with synchronic variation as the reflection and residue of language change. The empirical focus is the negation system of Fɛʔfɛʔ.
Sub Overig UiLOTS   +2 more
core   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Insights into the genome structure and copy-number variation of Eimeria tenella

open access: yesBMC Genomics, 2012
Background Eimeria is a genus of parasites in the same phylum (Apicomplexa) as human parasites such as Toxoplasma, Cryptosporidium and the malaria parasite Plasmodium.
Lim Lik-Sin   +4 more
doaj   +1 more source

Impact of genetic variation on three dimensional structure and function of proteins. [PDF]

open access: yesPLoS ONE, 2017
The Protein Data Bank (PDB; http://wwpdb.org) was established in 1971 as the first open access digital data resource in biology with seven protein structures as its initial holdings.
Roshni Bhattacharya   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Large-scale variation in combined impacts of canopy loss and disturbance on community structure and ecosystem functioning. [PDF]

open access: yes, 2013
Ecosystems are under pressure from multiple human disturbances whose impact may vary depending on environmental context. We experimentally evaluated variation in the separate and combined effects of the loss of a key functional group (canopy algae ...
Griffin Migné, JN   +125 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Understanding genome structural variations

open access: yesOncotarget, 2015
Genome structural variations (SVs) in the human genome are defined as DNA sequence polymorphisms of at least a few dozen or few hundred bases in length and include deletions, duplications, inversions, translocation, retroelement insertions, and more complex rearrangements that could be thought of as consisting of multiple fragments from the just listed
Abyzov, Alexej   +2 more
openaire   +2 more sources

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