Results 131 to 140 of about 1,017,462 (268)

Multi-scale resistivity imaging for soil moisture and structure characterization in precision agriculture. [PDF]

PLoS One
Widodo, Salam A, Fatkhan, Setiawan T.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Exploring the Siderophore Portfolio for Mass Spectrometry-Based Diagnosis of Scedosporiosis and Lomentosporiosis

ACS Omega
Jiří Houšt’, Andrea Palyzová, Tomáš Pluháček, Jiří Novák, Helena Marešová, Petr Hubáček, Radim Dobiáš, David A. Stevens, Hélène Guegan, Jean-Pierre Gangneux, Vladimír Havlíček   +10 more
doaj   +1 more source

Structure characterization with NMR molecular networking. [PDF]

Commun Chem
Stienstra CMK, Song J, Healey D, Voronov G, Gardner E, Patel A, Macherla V, Krettler CA, Kind T, Dorrestein PC, Domingo-Fernández D.   +10 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Structure characterization assists rational design of polyethyleneglycol diglycidyl ether (PEGDE) substituted hyaluronic acid. [PDF]

Synth Syst Biotechnol
Wu Y, Chen Y, Zhao S, Wan J, Su J, Kan Y, Li H, Li JP, Zhang T.   +8 more
europepmc   +1 more source

Three-Dimensional Pore Structure Characterization of Bituminous Coal and Its Relationship with Adsorption Capacity. [PDF]

Materials (Basel), 2023
Jia B, Li S, Dong K, Lin H, Cheng B, Wang K.   +5 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A Water-Soluble Polysaccharide from <i>Lophatherum gracile</i> Brongn.: Structure Characterization and Antitumor Activity In Vivo. [PDF]

Foods
Zhang X, Xing H, Liu H, Zhang X.
europepmc   +1 more source

X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences. [PDF]

ACS Bio Med Chem Au, 2023
Ogbonna EN, Paul A, Farahat AA, Terrell JR, Mineva E, Ogbonna V, Boykin DW, Wilson WD.   +7 more
europepmc   +1 more source