Results 41 to 50 of about 2,175,997 (287)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
The EU’s Consular Protection Policy from the Administrative Law Perspective
Central European Public Administration Review, 2020 The European Administrative Space has grown into a multi-level administrative structure characterised by the horizontal and vertical cooperation of all its levels.
Erzsébet Csatlós
doaj +1 more source
La protection des données de santé des athlètes dans le cadre de la lutte contre le dopage [PDF]
, 2006 Un résumé en anglais est également disponible.[À l'origine dans / Was originally part of : CRDP - Droit et technologies d'information et de communication]Le dopage fait l’objet d’une intense lutte par les autorités sportives.
Senécal, François
core +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Protección a la infancia y educacion en Castilla y León (1900-1930)
Aula, 2009 RESUMEN: El estudio que se presenta aborda las relaciones entre educación y protección de la infancia en Castilla y León en la baja restauración. Analizamos un conjunto de iniciativas institucionales que surgen en la sociedad y que tienen protección y ...
Leoncio VEGA GIL +3 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Utilisation de l’énergie solaire dans la protection cathodique de canalisations enterrées
Revue des Énergies Renouvelables, 2014 Les applications industrielles principales de la protection cathodique concernent les canalisations enterrées ou immergées. Le choix d’une méthode de protection contre la corrosion électrochimique se fait d’une part, selon le milieu environnant et d ...
F. Mohellebi +3 more
doaj
Human Trafficking and Terrorism: Utilizing National Security Resources to Prevent Human Trafficking in the Islamic State [PDF]
, 2014 This is a report of a Master’s thesis done in behalf of the local network in Stockholm, under Fortum Distribution AB. The thesis was to conduct a review of a distribution station named Fs Myrängen located in Täby.
Welch, Shannon A.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source