Results 61 to 70 of about 305,612 (264)

Solidarités environnementales, contestation transnationale et renouvellement de la politique mondiale

Lien Social et Politiques, 2007
L’ordre politique de la mondialisation est un champ conflictuel de relations économiques, culturelles et sociales au sein duquel les mouvements sociaux transnationaux construisent une nouvelle politique située au-delà des institutions traditionnelles ...
Carlos R. S. Milani, Ruthy Nadia Laniado
doaj   +1 more source

Familia y transmisión de valores

Teoría de la Educación: Revista Interuniversitaria, 2009
RESUMEN: En este artículo se hace una breve exposición de la «situación» de la familia en el contexto de la sociedad occidental. La «crisis» de la familia y los diferentes modelos de la estructura familiar son abordados, desde una perspectiva sociológica,
Pedro ORTEGA RUIZ, Ramón MÍNGUEZ VALLEJOS   +1 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Premiers éléments pour un dispositif de surveillance de l’état de conservation des habitats forestiers en France

Revue Forestière Française, 2016
La directive n° 92/43/CEE du 21 mai 1992, dite « directive Habitats, Faune, Flore », a introduit dans la politique de protection de la nature en Europe une notion de conservation d’un échantillon représentatif de certains habitats naturels présents sur ...
Fabienne Benest, Arnault Lalanne, Christian Gauberville, Jacques Drapier   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Etude des interactions mécaniques entre un bloc en mouvement et le milieu extérieur

Sciences, Eaux & Territoires, 2003
Les instabilités rocheuses figurent parmi les aléas rencontrés fréquemment en zone de montagne. Afin de réduire le risque associé, la stratégie dite passive vise à mettre en place des techniques de protection qui permettent de contrôler la trajectoire ...
F. NICOT
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Proteção do conhecimento e inovação: as amarras explícitas em uma universidade do Paraná │ Knowledge protection and innovation: the explicit ties in a university of Paraná, Brazil

Liinc em Revista, 2014
RESUMO O presente estudo procurou identificar o cenário para a proteção do conhecimento e inovação no meio acadêmico, bem como as dificuldades encontradas pelos pesquisadores no processo de patenteamento.
Adriana Aguillera Gonçalves, Maria Inês Tomaél   +1 more
doaj   +1 more source