Results 61 to 70 of about 307,034 (264)
L’ordre politique de la mondialisation est un champ conflictuel de relations économiques, culturelles et sociales au sein duquel les mouvements sociaux transnationaux construisent une nouvelle politique située au-delà des institutions traditionnelles ...
Carlos R. S. Milani, Ruthy Nadia Laniado
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Familia y transmisión de valores
RESUMEN: En este artículo se hace una breve exposición de la «situación» de la familia en el contexto de la sociedad occidental. La «crisis» de la familia y los diferentes modelos de la estructura familiar son abordados, desde una perspectiva sociológica,
Pedro ORTEGA RUIZ +1 more
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
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Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
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La directive n° 92/43/CEE du 21 mai 1992, dite « directive Habitats, Faune, Flore », a introduit dans la politique de protection de la nature en Europe une notion de conservation d’un échantillon représentatif de certains habitats naturels présents sur ...
Fabienne Benest +3 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
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Etude des interactions mécaniques entre un bloc en mouvement et le milieu extérieur
Les instabilités rocheuses figurent parmi les aléas rencontrés fréquemment en zone de montagne. Afin de réduire le risque associé, la stratégie dite passive vise à mettre en place des techniques de protection qui permettent de contrôler la trajectoire ...
F. NICOT
doaj
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
RESUMO O presente estudo procurou identificar o cenário para a proteção do conhecimento e inovação no meio acadêmico, bem como as dificuldades encontradas pelos pesquisadores no processo de patenteamento.
Adriana Aguillera Gonçalves +1 more
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