Results 41 to 50 of about 307,034 (264)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Protection sociale, structures marchandes et temporalité de l'activité. Pigistes et comédiens face à l'assurance-chômage [PDF]
Sociologie, 2010 Résumé L’étude des populations artistiques met en évidence le rôle de la protection sociale, et notamment de l’assurance- chômage, dans le cas des carrières « par projets ». L’analyse conjointe d’une population de comédiens et de pigistes permet de revenir sur ce résultat en montrant que les dispositifs de protection sociale ne sont pas nécessairement ...
openaire +1 more source
Influence des tanins sur la valeur nutritive des aliments des ruminants
INRAE Productions Animales, 1996 Les tanins sont des métabolites secondaires importants dans le règne végétal. Ils s’intègrent dans la défense des végétaux contre les herbivores, en particulier pour les plantes se développant dans les zones difficiles.
N. ZIMMER, R. CORDESSE
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Structures with chloride attack. Application of cathodic protection in the bridge to Illa de Arousa
Hormigón y Acero, 2017 Abstract The bridge of this project is a reinforced concrete structure of 1980 m divided in 40 spans. The deck is a single-cell box girder and a total width of 13 m including sidewalks and shoulders. After 25 years in marine environment, the structure showed reinforcement corrosion, especially in piles and deck bottom.
José Antonio Becerra Mosquera +3 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Conception et comportement dynamiques des structures de génie civil : application aux ouvrages paravalanches Behaviour and design of civil engineering structures exposed to dynamic loads: the case of snow avalanches defence works [PDF]
Sciences, Eaux & Territoires, 2010 Optimiser la conception des ouvrages de protection contre les avalanches est une priorité pour la sécurité en montagne. Les auteurs nous démontrent ici comment la discipline du génie civil contribue à améliorer les connaissances sur le comportement des ...
Jean-Marc Tacnet, Emmanuel Thibert, Philippe Berthet-Rambaud, Ali Limam, Mohamed Naaim, Pascal Perrotin et Didier Richard
doaj
Éducation et Socialisation, 2000 Dans cet article, les auteurs présentent tout d’abord l’évolution du construit de résilience, à la fois selon ses fondements épistémologiques et sous l’angle du rapport contextuel existant entre le concept de risque et celui de protection. La perspective
Bernard Terrisse +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source