Results 81 to 90 of about 2,175,997 (287)

State of the issue and new challenges of Social Work: reflections of recently graduated professionals from Peru and Spain [PDF]

open access: yes, 2019
Currently the primacy of the market economy in most of the nations is constituted as a global phenomenon, which has direct consequences on the structure of the different states socio-political systems.
Domínguez de la Rosa, Laura   +1 more
core  

Corrosion Resistance of Steel/Zinc with Silicate Nanoparticles/Polyurethane Paint Systems in NaCl Solution [PDF]

open access: yes, 2012
Surface characteristics and corrosion behaviour of bare electrogalvanized steel coated with polymer/nano-silicate particles added to the electrogalvanizing bath were studied by scanning electron microscopy (SEM), energy dispersive spectrometer (EDXS) and
Di Sarli, Alejandro Ramón   +2 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

The Economics of Life ++ - Reflections on the Term of Copyright [PDF]

open access: yes
Copyright, and indeed all intellectual property, reflects a compromise between the need for reward on creations we see – by reserving them to the creator – and the need to let information freely flow so as to permit further creations to emerge with as ...
Ejan Mackaay
core  

Spatial genetic structure in the saddled sea bream (Oblada melanura [Linnaeus, 1758]) suggests multi-scaled patterns of connectivity between protected and unprotected areas in the Western Mediterranean Sea [PDF]

open access: yes, 2016
Marine protected areas (MPAs) and networks of MPAs are advocated worldwide for the achievement of marine conservation objectives. Although the knowledge about population connectivity is considered fundamental for the optimal design of MPAs and networks ...
Calo A.   +4 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Premiers éléments pour un dispositif de surveillance de l’état de conservation des habitats forestiers en France

open access: yesRevue Forestière Française, 2016
La directive n° 92/43/CEE du 21 mai 1992, dite « directive Habitats, Faune, Flore », a introduit dans la politique de protection de la nature en Europe une notion de conservation d’un échantillon représentatif de certains habitats naturels présents sur ...
Fabienne Benest   +3 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

La mise en application d’un règlement de protection animale au regard de la structuration des abattoirs français

open access: yesAnthropology of food, 2019
Le processus d’industrialisation a transformé les abattoirs jusqu’à aboutir à deux modèles relativement distincts : des grands sites privés qui ne cessent d’accroître leur volume d’abattage et des petits établissements à faible production qui assurent un service de prestation dans une localité donnée. La mise en œuvre du règlement de protection animale
Jourdan, Félix, Hochereau, François
openaire   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

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