Results 91 to 100 of about 306,884 (301)
Magnetochemistry, 2018 Structural characterization of complexes is crucial for a better understanding of biological processes and structure-based drug design. However, many protein–ligand structures are not solvable by X-ray crystallography, for example those with low affinity
Marielle Aulikki Wälti, Julien Orts
doaj +1 more source
SOME PHENOLIC COMPOUNDS FROM STEM BARK OF MELINJO (GNETUM GNEMON) AND THEIR ACTIVITY TEST AS ANTIOXIDANT AND UV-B PROTECTION [PDF]
Isolation and structure elucidation of three phenolic compounds, namely 3,4-dimethoxychlorogenic acid (1), resveratrol (2), and 3-methoxyresveratrol (3) from stem bark of Melinjo (Gnetum gnemon) had been done. The isolation of those compounds was carried
Sri , Atun, Ph.D
core
Discovery of a family of γ-aminobutyrate ureas via rational derepression of a silent bacterial gene cluster [PDF]
, 2013 Gaburedins, a family of γ-aminobutyrate (GABA)-derived ureas, have been discovered by deletion of gbnR, an arpA-like putative transcriptional repressor in Streptomyces venezuelae ATCC 10712.
Arakawa +20 more
core +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Isolation of two steroidal saponins with antileishmanial activity from Allium giganteum L.
Research in Pharmaceutical SciencesBackground and purpose: Alliums are rich sources of steroidal saponins, flavonoids, and sulphoric compounds of which steroidal saponins have recently received more attention due to their important pharmacological activities. Allium giganteum (giant onion)
Farnaz Chaparian +2 more
doaj +1 more source
Gravitational Billiards, Dualities and Hidden Symmetries
, 2005 The purpose of this article is to highlight the fascinating, but only very incompletely understood relation between Einstein's theory and its generalizations on the one hand, and the theory of indefinite, and in particular hyperbolic, Kac Moody algebras ...
Nicolai, H.
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
New microbial source of the antifungal allylamine “Terbinafine”
Saudi Pharmaceutical Journal, 2017 The isolated active compound “F12” from the culture media of the Streptomyces sp. KH-F12 was identified using different spectroscopic techniques. Both 1D- and 2D-NMR as well as HRESIMS were utilized to characterize the structure of the isolated compound.
Maged S. Abdel-Kader, Magdy M. Muharram
doaj +1 more source
Journal of Fungi, 2020 The genus Stromatoneurospora was erected in 1973 by Jong and Davis to accommodate the pyrophilic pyrenomycete Sphaeria phoenix and has traditionally been placed in the family Xylariaceae based on morphological features. However, no living culture of this
Kevin Becker +5 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source