Results 201 to 210 of about 121,928 (262)

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

Bioassay-guided isolation and structure elucidation of anti-mycobacterium tuberculosis compounds from Galatella grimmii (Regel & Schmalh.) Sennikov. [PDF]

open access: yesBMC Complement Med Ther
Shakeri A   +7 more
europepmc   +1 more source

A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst. [PDF]

open access: yesNat Commun
Schönherr R   +11 more
europepmc   +1 more source

Elucidating ‘undecipherable’ chemical structures using computer‐assisted structure elucidation approaches [PDF]

open access: yesMagnetic Resonance in Chemistry, 2012
Structure elucidation using 2D NMR data and application of traditional methods of structure elucidation are known to fail for certain problems. In this work, it is shown that computer‐assisted structure elucidation methods are capable of solving such problems.
Mikhail E Elyashberg, Antony J Williams
exaly   +3 more sources
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Structure Elucidation of Antibiotics

2022
To date, there are hundreds of characterized natural products with antibacterial activity against pathogenic bacteria, and several have become bonafide antibiotic drugs. The development of antibacterial natural products into antibiotic drugs, both in the past and in the future, hinges upon an accurate description of the exact chemical structure of the ...
Julia, Moschny   +3 more
openaire   +2 more sources

The Structure Elucidation of Pseudothiocolchicine

Helvetica Chimica Acta, 1985
AbstractA colchicine derivative, previously isolated from the reaction of isocolchicine with sodium thiomethoxide in aqueous MeOH, was now identified as 11‐(methylthio)isocolchicine on the basis of 1H‐, 13C‐NMR spectra and chemical correlation. This reaction represents the first example of abnormal nucleophilic displacement (telesubstitution) in the ...
B. DANIELI   +3 more
openaire   +2 more sources

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