Results 21 to 30 of about 121,928 (262)

Elsinopirins A–D, Decalin Polyketides from the Ascomycete Elsinoё pyri

Biomolecules, 2018
In course of our screening for new secondary metabolites from ecological niche specialized, phytopathogenic fungi, the plant pathogen Elsinoё pyri, strain 2203C, was found to produce four novel compounds (1–4), which were named elsinopirins A–D, in ...
Frank Surup, Kathrin Pommerehne, Hans-Josef Schroers, Marc Stadler   +3 more
doaj   +1 more source

Characterization and Diversity of Microcystins Produced by Cyanobacteria from the Curonian Lagoon (SE Baltic Sea)

Toxins, 2021
Microcystins (MCs) are the most widely distributed and structurally diverse cyanotoxins that can have significant health impacts on living organisms, including humans.
Donata Overlingė, Anna Toruńska-Sitarz, Marija Kataržytė, Renata Pilkaitytė, Greta Gyraitė, Hanna Mazur-Marzec   +5 more
doaj   +1 more source

The Evolving Landscape of NMR Structural Elucidation

Molecules
Nuclear Magnetic Resonance (NMR) spectroscopy has long been a cornerstone in the structural elucidation of molecules, offering unique insights into atomic-level connectivity, conformation, and dynamics.
Josep Saurí
doaj   +1 more source

Antileishmanial Activity of  New Steroidal Saponin Isolated from the Flowers of Allium Austroiranicum [PDF]

Journal of Advanced Biomedical Sciences, 2022
Background & Objective: Plants are reservoirs of bioactive compounds, which are known to be chemically balanced, effective and least injurious as compared to synthetic medicines.
Zeinab Delazar, Mahrouz Ashrafi Rahaghi, Masoud Sadeghi Dinani   +2 more
doaj  

Sampling CASE Application for the Quality Control of Published Natural Product Structures

Molecules, 2021
Structure elucidation with NMR correlation data is dicey, as there is no way to tell how ambiguous the data set is and how reliably it will define a constitution.
Lorena Martins Guimarães Moreira, Jochen Junker   +1 more
doaj   +1 more source

6,7,8,9-Tetrafluoro-11H-indeno[1,2-b]quinoxalin-11-one

Molbank
Fluorinated aza-heterocycles are important in organic and medicinal chemistry. Currently, a quarter of the drugs on the global market contain fluorine. We report the synthesis of the title compound and its single-crystal XRD structure.
Anastasia R. Kovrizhina, Irina Yu. Bagryanskaya, Andrey V. Zibarev, Andrei I. Khlebnikov   +3 more
doaj   +1 more source

Synthesis and Structure Elucidation of 4-(4-Amino-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl-methylene)-2-phenyl-1H-imidazol-5(4H)-one

E-Journal of Chemistry, 2010
4-(4-Amino-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl-methylen)-2-phenyl-1(3H)-imidazol-5-one (5) was synthesized in four steps in high yield.
Hooshang Vahedi, Navabeh Nami, Nasrin Nami   +2 more
doaj   +1 more source

Blind trials of computer-assisted structure elucidation software

Journal of Cheminformatics, 2012
Background One of the largest challenges in chemistry today remains that of efficiently mining through vast amounts of data in order to elucidate the chemical structure for an unknown compound.
Moser Arvin, Elyashberg Mikhail E, Williams Antony J, Blinov Kirill A, DiMartino Joseph C   +4 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Enantiomeric characterization and structure elucidation of Otamixaban

Journal of Pharmaceutical Analysis, 2014
Otamixaban is a potent (Ki=0.5 nM) fXa inhibitor currently in late-stage clinical development at Sanofi for the management of acute coronary syndrome.
Jian Shen, Jiping Yang, Winfried Heyse, Harald Schweitzer, Norbert Nagel, Doris Andert, Chengyue Zhu, Vincent Morrison, Gregory A. Nemeth, Teng-Man Chen, Zhicheng Zhao, Timothy A. Ayers, Yong-Mi Choi   +12 more
doaj   +1 more source