Results 161 to 170 of about 3,832,797 (315)

A Network Structure of Mental Health and Problematic Mobile Phone Use Among Middle School Students [PDF]

open access: yes
Mingwan Zhou,1 Xueti Dong,2 Weige Wu,3,4 Yun Li4,5 1Psychological Assessment Center, Xiamen Xianyue Hospital, Xianyue Hospital Affiliated with Xiamen Medical College, Fujian Psychiatric Center, Fujian Clinical Research Center for Mental Disorders, Xiamen,
Zhou M, Li Y, Dong X, Wu W
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Sustainable Planning of Land Use Changes in farming areas under ecological protection [PDF]

open access: yes, 2010
Land use has been changing in the last decades because of agricultural intensification and land abandonment which implies deterioration in the optimum habitat structure and quality.
Montero-Riquelme, F.   +3 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Beyond unobserved heterogeneity in computer wage premiums / Data on computer use in Germany, 1997 – 2001 [PDF]

open access: yes
Beyond unobserved heterogeneity in computer wage premiums: Most findings on the (non-)existence of a wage premium on computer use are biased because they are based on single-equation estimation of a wage equation.
Muysken, Joan   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Computer Use and Earnings [PDF]

open access: yes
This paper uses longitudinal data for the UK to investigate the observed correlation between computer use at work and labor market earnings. Our findings suggest that there are no returns to computer use at work. This is evidence against the productivity
Mary A. Silles
core  

STRUCTURE, COMPOSITION AND USE OF TREES OF THE DECIDUOUS FOREST IN APATZINGAN, MICHOACAN

open access: yesTropical and Subtropical Agroecosystems, 2014
The aim of this study was to determine the structure, composition and use of trees and shrubs of tropical deciduous forest in the mountains of Apatzingán, Michoacan.
F. Casanova-Lugo   +3 more
doaj  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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