YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Re: "A novel splice-altering frameshift variant in the COL1A1 gene underlies osteogenesis imperfecta type I: molecular characterization of a four-generation Chinese pedigree and literature review". [PDF]
Dalgleish R.
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
A tutorial on causal network simulation and exploration using the causalnet R package. [PDF]
Park K, Vasconcelos VV, Lees M.
europepmc +1 more source
Supporting human-agent communication for explainable planning in spatial-temporal planning problems. [PDF]
Lindsay A +7 more
europepmc +1 more source
Cross-cultural adaptation and psychometric evaluation of the artificial intelligence learning intention scale (AILIS) among medical sciences students: a methodological study. [PDF]
Taghiparast AH +3 more
europepmc +1 more source
Land-Use Effects on Melliferous Woody Flora in Sudanian Agroforestry Parkland and Protected Area of West Africa. [PDF]
Kanazoe IW +3 more
europepmc +1 more source
Toward a standardized and interoperable imaging biomarker catalog. [PDF]
Rodríguez-Belenguer P +10 more
europepmc +1 more source
Gas Permeability of the Anisotropic Structure of a Frame Made of Concrete with the Addition of a Biocomponent-Application in Livestock Buildings. [PDF]
Janowska-Renkas E +5 more
europepmc +1 more source

