Results 21 to 30 of about 40,352 (207)

Magnetic circular dichroism versus orbital magnetization

open access: yesPhysical Review Research, 2020
The magnetic circular dichroism sum rule yields an extremely useful ground-state observable, which provides a quantitative measure of spontaneous time-reversal symmetry breaking (T-breaking) in a given material.
Raffaele Resta
doaj   +1 more source

THE NON-COPRIME GRAPHS OF UPPER UNITRIANGULAR MATRIX GROUPS OVER THE RING OF INTEGER MODULO WITH PRIME ORDER AND THEIR TOPOLOGICAL INDICES

open access: yesBarekeng
In its application graph theory is widely applied in various fields of science, including scheduling, transportation, industry, and structural chemistry, such as topological indexes.
M. Afdhaluzzikri   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Clustering-independent analysis of genomic data using spectral simplicial theory.

open access: yesPLoS Computational Biology, 2019
The prevailing paradigm for the analysis of biological data involves comparing groups of replicates from different conditions (e.g. control and treatment) to statistically infer features that discriminate them (e.g.
Kiya W Govek   +2 more
doaj   +1 more source

Functional Molecular Ecological Networks

open access: yesmBio, 2010
Biodiversity and its responses to environmental changes are central issues in ecology and for society. Almost all microbial biodiversity research focuses on “species” richness and abundance but not on their interactions.
Jizhong Zhou   +5 more
doaj   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao   +6 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

On automorphism groups of Toeplitz subshifts

open access: yesDiscrete Analysis, 2017
On automorphism groups of Toeplitz subshifts, Discrete Analysis 2017:11, 19 pp. A discrete dynamical system is a space $X$ with some kind of structure, together with a map $\sigma\colon X\to X$ that preserves the structure.
Sebastian Donoso   +3 more
doaj   +1 more source

Representation of Topology Using Homology Groups and Its Application to Structural Optimization. Fitness Value Based upon Topology for Unanalyzable Structures Generated in Genetic Algorithm and Its Effect on Performance of Optimization.

open access: yesJSME International Journal Series A, 2000
Genetic algorithm (GA) is one of the most useful methods to optimize topology of structures. The performance of GA, however, deeply depends upon a rule of coding from a structure to a string (a chromosome), which must be decided before the execution of GA.
openaire   +2 more sources

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