Results 31 to 40 of about 40,825 (244)

Clustering-independent analysis of genomic data using spectral simplicial theory.

open access: yesPLoS Computational Biology, 2019
The prevailing paradigm for the analysis of biological data involves comparing groups of replicates from different conditions (e.g. control and treatment) to statistically infer features that discriminate them (e.g.
Kiya W Govek   +2 more
doaj   +1 more source

Functional Molecular Ecological Networks

open access: yesmBio, 2010
Biodiversity and its responses to environmental changes are central issues in ecology and for society. Almost all microbial biodiversity research focuses on “species” richness and abundance but not on their interactions.
Jizhong Zhou   +5 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

On topological and algebraic structure of extremally disconnected semitopological groups [PDF]

open access: yes, 2000
summary:Starting with a very simple proof of Frol'\i k's theorem on homeomorphisms of extremally disconnected spaces, we show how this theorem implies a well known result of Malychin: that every extremally disconnected topological group contains an open ...
Arhangel'skii, A. V.
core  

Representation of Topology Using Homology Groups and Its Application to Structural Optimization. Fitness Value Based upon Topology for Unanalyzable Structures Generated in Genetic Algorithm and Its Effect on Performance of Optimization.

open access: yesJSME International Journal Series A, 2000
Genetic algorithm (GA) is one of the most useful methods to optimize topology of structures. The performance of GA, however, deeply depends upon a rule of coding from a structure to a string (a chromosome), which must be decided before the execution of GA.
openaire   +2 more sources

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez   +5 more
wiley   +1 more source

On automorphism groups of Toeplitz subshifts

open access: yesDiscrete Analysis, 2017
On automorphism groups of Toeplitz subshifts, Discrete Analysis 2017:11, 19 pp. A discrete dynamical system is a space $X$ with some kind of structure, together with a map $\sigma\colon X\to X$ that preserves the structure.
Sebastian Donoso   +3 more
doaj   +1 more source

Composition‐Tuned Enhancement of the Anomalous Nernst Effect in FeCo–Pt Thin Films on Rigid and Flexible Substrates

open access: yesAdvanced Engineering Materials, EarlyView.
Disordered (Fe50Co50)1−xPtx thin films exhibit a pronounced anomalous Nernst effect (ANE) with a strong composition dependence on both rigid and flexible substrates. The transverse thermoelectric response peaks near 22.5 at.% Pt, accompanied by enhanced αxy/σxy scaling, thermal transport, and ANE sensitivity.
Mojtaba Mohammadi   +2 more
wiley   +1 more source

Additive Manufacturing of Continuous Fibre Reinforced Composites: Process, Characterisation, Modelling, and Sustainability

open access: yesAdvanced Engineering Materials, EarlyView.
Additive manufacturing provides precise control over the placement of continuous fibres within polymer matrices, enabling customised mechanical performance in composite components. This article explores processing strategies, mechanical testing, and modelling approaches for additive manufactured continuous fibre‐reinforced composites.
Cherian Thomas, Amir Hosein Sakhaei
wiley   +1 more source

Direct Metal Deposition of Graphene–Ti28Nb35.4Zr Matrix Composites With Enhanced Mechanical, Corrosion, and Biocompatibility Properties for Bone Implants

open access: yesAdvanced Engineering Materials, EarlyView.
Graphene nanoplatelet (0.1 wt.%) reinforcement significantly enhances the performance of β Ti‐28Nb‐35.4Zr alloy. Grain refinement, reduced water contact angle, and improved surface characteristics promote osteoblast adhesion and complete surface coverage after 7 days.
Khurram Munir   +5 more
wiley   +1 more source

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