Results 81 to 90 of about 3,924,108 (319)
ICRSSD: Identification and Classification for Railway Structured Sensitive Data
Future InternetThe rapid growth of the railway industry has resulted in the accumulation of large structured data that makes data security a critical component of reliable railway system operations. However, existing methods for identifying and classifying often suffer
Yage Jin +4 more
doaj +1 more source
Imaging of shallow structures around Küçükçekmece Lake in Istanbul land area with high resolution geophysical data. [PDF]
, 2021 Hakan Alp +3 more
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
nDeepSMOTEc: An Oversampling Method for Structured Datasets
IEEE AccessThe problem of imbalanced data is pervasive in the field of machine learning, particularly in applications such as medical diagnosis and fraud detection, where minority class samples are crucial for accurate model predictions.
Wen-Lin Fan +5 more
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The Algebraic Operations and Their Implementation Based on a Two-Layer Cloud Data Model
Cybernetics and Information Technologies, 2016 The existing cloud data models cannot meet the management requirements of structured data very well including a great deal of relational data, therefore a two-layer cloud data model is proposed. The composite object is defined to model the nested data in
Li Ying, Dong Baotian
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Internet Archaeology'Big Data' is a misunderstood but technically definable concept; it is large volume, unstructured, heterogenous information, that is being generated at a high velocity - which normally means it is being constantly updated in real time.
Kenneth Aitchison
doaj +1 more source