Results 71 to 80 of about 1,710,525 (287)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Structured Light Beams: Science and Applications

open access: yesPhotonics
Coherent structured light beams are developed by producing non-uniform phases and inducing polarization distribution in the cross-section of laser beams [...]
Andra Naresh Kumar Reddy   +1 more
doaj   +1 more source

Polarisation structuring of broadband light [PDF]

open access: yesOptics Express, 2017
Spatial structuring of the intensity, phase and polarisation of light is useful in a wide variety of modern applications, from microscopy to optical communications. This shaping is most commonly achieved using liquid crystal spatial light modulators (LC-SLMs).
Mitchell, Kevin J.   +4 more
openaire   +2 more sources

Nonlinear propagation of light in structured media: generalized unidirectional pulse propagation equations

open access: yes, 2012
Unidirectional pulse propagation equations [UPPE, Phys. Rev. E 70, 036604 (2004)] have provided a theoretical underpinning for computer-aided investigations into dynamics of high-power ultrashort laser pulses and have been successfully utilized for ...
Andreasen, J., Kolesik, M.
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structured light meets machine intelligence

open access: yeseLight
Structured light, where light is tailored in all its degrees of freedom, has shown tremendous power in unlocking new modalities of light, with its impact felt across dimensions, disciplines, and applications.
Zilong Zhang   +10 more
doaj   +1 more source

Optical Singularities in Photonic Microstructures with Rosette Symmetries: A Unified Theoretical Scheme

open access: yesEngineering
Optical singularities are topological defects of electromagnetic fields; they include phase singularity in scalar fields, polarization singularity in vector fields, and three-dimensional (3D) singularities such as optical skyrmions.
Jie Yang   +5 more
doaj   +1 more source

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