Results 81 to 90 of about 29,034 (256)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Transforming Property Tax Governance: A Spatially Adaptive Land Value Determination (SALAD) Model for Fiscal Cadastre Modernization

Geographies
Property taxation serves as a critical instrument for fiscal efficiency and equitable distribution, yet implementation faces significant challenges including valuation inaccuracies, insufficient administrative capacity, and diminished public trust ...
Andri Hernandi, Irwan Meilano, Asep Yusup Saptari, Deni Suwardhi, Rizqi Abdulharis, Alfita Puspa Handayani, Sella Lestari Nurmaulia, Nabila Sofia Eryan Putri, Ratri Widyastuti, Putri Merdekawati, Fitri Nur Cahyani   +10 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Representations over diagrams of abelian categories I: Global structure and homological objects

Journal of Algebra
Representations over diagrams of abelian categories unify quite a few notions appearing widely in literature such as representations of categories, presheaves of modules over categories, representations of species, etc. In this series of papers we study them systematically, characterizing special homological objects in representation category and ...
Zhenxing Di, Liping Li, Li Liang, Nina Yu   +3 more
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Human Communication-Inspired Semantic–View Collaborative Network for Multispectral Remote Sensing Image Retrieval

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Multispectral images (MSIs) have widespread applications, and efficiently managing these extensive MSIs via remote sensing image retrieval (RSIR) is key to boosting their practical value.
Nan Wu, Wei Jin, Randi Fu
doaj   +1 more source

The pattern of elementary teachers' insight in online education, using foundational data theory [PDF]

مدیریت و چشم انداز آموزش
The aim of the current research is to design the model of elementary teachers' insight in online education based on the data-based theory. The statistical population of the research includes elites and experts in the field of curriculum planning and ...
reyhaneh bazrafshan delijan, Mohammad Ghafari Mejlej, seyyed javad mortazavi amiri   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

GPOD: Geographic Priors and Object Detection for Candidate-Guided Target Localization in City-Scale UAV Vision-and-Language Navigation

Drones
City-scale unmanned aerial vehicle vision-and-language navigation (UAV-VLN) requires accurate upstream target localization from an overhead map, onboard observation, and language description.
Yuze Liu, Changming Xu, Kewen Xiao, Yuhua Wu, Ziyu Li   +4 more
doaj   +1 more source