Results 101 to 110 of about 441,298 (300)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Social Work and Society, 2011 At the beginning of the 20th century, Bulgaria as a part of the Balkan and South East European region was a a typical rural country of small and middle scale farming and prevailing peasant population.At the beginning of the 20th century, many rural ...
Kristina Popova
doaj +2 more sources
How recurrent floods create inequality in livelihood improvement through education
Humanities & Social Sciences CommunicationsEducation is a powerful tool against poverty and inequality, yet its potential is undermined by floods. While floods do not affect the population equally, previous studies have ignored the chronic impact of recurrent flooding on education across ...
Leon Vin +2 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Imperialism, dependency, and social class [PDF]
, 1981 African Studies Center Working Paper No. 45INTRODUCTION: The purpose of this essay is to examine what has become known in the language of post-World War II social science as "dependency theory." Although all variants of this dependency theory are more or
Hansen, William, Schulz, Brigitte
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Color/Identity/Justice: Chicano Trials [PDF]
, 2004 This Book Review seeks to rectify in small measure the omission of color from American documents of black/white legal and political struggle. Enlarging the spectrum of struggle beyond the black/white paradigm not only works to correct the historical ...
Alfieri, Anthony V.
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Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
HUMAN TRAFFICKING – SLAVERY OF THE 21st CENTURY [PDF]
Hum, 2017 This paper deals with human trafficking which is a complex social phenomenon whose dynamics, mobility and organization in national and international dimensions represents a complex and serious problem of contemporary society.
Irena Musa
doaj
8. The National State in Spain
, 1958 The third national state and strong monarchy to be established by the end of the fifteenth century was in Spain. Separated from the rest of the Continent by the lofty and forbidding Pyrenees, Spanish culture developed in relative isolation from the main ...
Bloom, Robert L. +6 more
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