Results 141 to 150 of about 12,309 (251)

Level and determinants of district primary healthcare system technical efficiency in Ghana: two-stage stochastic frontier analysis. [PDF]

BMJ Glob Health
Amboko B, Novignon J, Muthuri RNDK, Bozzani FM, Vassall A, Barasa E.   +5 more
europepmc   +1 more source

joining people in their struggle against poverty

, 2013
openaire   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Maternal Cancer Mortality and Orphanhood: A Neglected Global Health and Equity Challenge. [PDF]

Ann Glob Health
Francis DL.
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Stratifying areas at risk of housing insecurity among families with children: a multidimensional index for the improvement of policy interventions in England. [PDF]

BMC Public Health
O'Brien J, Coombes E, Burn AM, Fairbrother H, Holding E, Woodrow N, Rodgers SE.   +6 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Climate change, livelihoods, gender and violence in Rukiga, Uganda: Intersections and pathways. [PDF]

PLOS Glob Public Health
Muhumuza R, Colombini M, Zilstorf P, Collee I, Namanya G, Katongole J, Mayhew S.   +6 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

A Scoping Review on the Impact of the Environment on Racialized Immigrant Older Adults' Social Connectedness and Sense of Belonging. [PDF]

J Aging Res
Puplampu VA, Ho AHY, Kazi M, Baffour-Awuah A, Dalidowicz M, Bushi J, Salma J, Osuji J, Moasun FY, Chipanshi M, Luhanga F, Falihi A, Nsaliwa C, Pierson J, Mambu LM, Salami B.   +15 more
europepmc   +1 more source