Results 151 to 160 of about 5,098,783 (294)

The social programs of struggle against the extreme poverty in the province of Leoncio Prado – 2005

, 2009
El presente estudio tiene como ámbito geográfico la Provincia de Leoncio Prado en la Región Huánuco. El análisis estuvo referido a los programas sociales que tienen como misión contribuir a elevar el nivel alimentario y nutricional de grupos en situación de pobreza extrema, focalizando como primera prioridad a niños de cero a 7 años, madres gestantes y
Villaizán y Huerto, Jorge, Torres Velásquez, César A., Esteban Churampi, Efraín, Bazán Rivera, Jimmy   +3 more
openaire   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Incomplete assessments: Including harms and trade-offs in assessing policy approaches to Covid-19. [PDF]

SSM Popul Health
Bavli I, Sutton B, Bardosh K, Galea S.
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

To the Struggle Against World Terrorism

, 2011
To the Struggle Against World Terrorism 9-11 teardrop 1.jpeg The sculpture comprises a 100-foot bronze-clad tower split with a jagged opening in the middle, in which hangs a 40-foot tall nickel-surfaced teardrop.
Beards, Daniel E.
core  

A Bourdieusian Approach to the Demobilisation of Brazil's AIDS Movement. [PDF]

Sociol Health Illn
Achcar HM.
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Regional seminars as part of Ireland's national programme for the 2010 European year for combating poverty and social exclusion

, 2011
As part of the Irish National programme for the 2010 European Year for Combating Poverty and Social Exclusion, a series of five regional seminars were organised by the Community Workers’ Co-operative, the European Anti-Poverty Network and the Community ...
Community Workers’ Co-operative, European Anti-Poverty Network, Community Platform   +2 more
core  

Comprehensive approaches to Traumatic Brain Injury: bridging physical, emotional, and social dimensions for global health care. [PDF]

Ann Med
Edward M, Takoutsing B, Ogunfolaji O, Nyakara D, KoulagnaBoris G.   +4 more
europepmc   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source