A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Illness to poverty in India: a qualitative exploration of hardship financing for healthcare. [PDF]
Thomas AR, Sahu SK, Dash U.
europepmc +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Emotion regulation strategies among young men in rural areas and urban informal settlements in South Africa: a qualitative exploratory study. [PDF]
Nyoni P, Tomita A, Mkhwanazi S, Gibbs A.
europepmc +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Psychological distress and associated factors among South Asian individuals with chronic obstructive pulmonary disease: a convergent mixed methods study. [PDF]
Zeb H, Younas A, Durante A, Vellone E.
europepmc +1 more source
Recognizing threat and assuming responsibility: tobacco control in Armenia [PDF]
Lalayan, Sevak
core
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
Intersecting inequities: a systematic review of socio-cultural, economic, and legal determinants of violence against women and girls in Asia (ANULA project-WP1 Evidence Synthesis). [PDF]
Wijamuni N +9 more
europepmc +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source

