Results 151 to 160 of about 13,908,878 (285)

Towards State of the Science in Person-Centred Care [PDF]

open access: yes
This report aims to take first steps in reporting the state of the science in person-centered care: an idea focusing on how health professionals, patients and their family carer(s) collaboratively plan and carry out care.

core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Developing a student centred approach to practice placement briefings and debriefings [PDF]

open access: yes, 2007
This research developed from the recognition that work-based placement briefing and debriefing sessions need to encourage reflection and student self-directed learning. An action research methodology was used to obtain students views of the value of briefing and debriefing sessions.
openaire  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Advancing Person-Centred Learning in Higher Education: Reflections and Lessons from the LearnPCC Conference

open access: yes
LearnPCC scientific conference held in Gothenburg, Sweden, on 12–13 December 2024The inaugural LearnPCC scientific conference was held in Gothenburg, Sweden, on 12–13 December 2024. Organised by the Centre for Person-Centred Care (GPCC) at the University
LearnPCC Conference 1 2024 Göteborg
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Home - About - Disclaimer - Privacy