Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Rearrangement of mentoring components for Student Achievement of medical universities. [PDF]
J Adv Med Educ Prof, 2022 Keykha A, Keykha E.
europepmc +1 more source
Pursuing the Principalship: Factors in Assistant Principals’ Decisions [PDF]
, 2018 School administrators who are hired to lead and guide schools and districts must possess a number of characteristics that allow them to become successful leaders.
Brown, Casey Graham, Ellis, Amy
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
An innovative approach for graduate nursing student achievement of leadership, quality, and safety competencies. [PDF]
J Prof Nurs, 2022 Horowitz ML +4 more
europepmc +1 more source
Leadership Matters: Building Leadership Capacity [PDF]
, 2001 Explores strategies that school administrators employ in schools where student learning has improved. Outlines the key conditions for accelerating student achievement, and provides criteria for determining the quality of project-based ...
Carol H. Feagin +3 more
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Multi-Layer Perception model with Elastic Grey Wolf Optimization to predict student achievement. [PDF]
PLoS One, 2022 Song Y, Meng X, Jiang J.
europepmc +1 more source
Our Children Can't Wait: A Proposal to Close the Middle-Grades Achievement Gap [PDF]
, 2008 This report seeks to answer the question: How much has Children First improved student achievement in literacy in the middle grades? How successful has Children First been in closing the race and poverty achievement gaps in literacy in the middle ...
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source