Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
How Does Teacher Certification Promote Student Achievement in Science, Reading, and Math? A Chain-Mediated Model of Teachers' Sense of Efficacy and Pedagogical Innovation. [PDF]
J IntellGuo Y, Tian G.
europepmc +1 more source
Comparing student achievement in traditional learning with a combination of blended and flipped learning. [PDF]
Nurs Open, 2020 Halasa S +7 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The effect of stand-your-ground laws on student achievement. [PDF]
Prev Med RepRuffini K, Roan Gresenz C, Gordon N.
europepmc +1 more source
Exploring the Impact of Student Teaching Apprenticeships on Student Achievement and Mentor Teachers. [PDF]
J Res Educ Eff, 2020 Goldhaber D, Krieg JM, Theobald R.
europepmc +1 more source
Achievement Patterns Of Students In An Elite, Male Independent School
, 2009 Edward Maurice Trusty
openalex +1 more source
Vestigation of the secondary school students’ non routine mathematical problem solving achievement on the context of beliefs towards mathematical problem solving [PDF]
, 2023 Özlem Elmas
openalex