Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Determinants of Student Governments’ Promotional Activity
Marketing of Scientific and Research Organizations, 2018 The subject of marketing activity of students’ governments hasn’t been present in scientific literature up till now. There have been only few publications devoted to chosen areas of functioning of students’ organizations.
Bryk Justyna, Gębarowski Marcin
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Reforming Mathematic Through The Concept Of Cooperative Learning By Using The Technique Think-Pair-Share Focusing On Cube And Cuboid To Improve The Study Result And Activity Of Students From Banyubiru 1 State Middle School Class Of Viiie In Semarang District On Their Second Semester Year Of 2010/2011 [PDF]
, 2011 Determining the use of mathematical model is very influential on students’ study outcomes and activity. In deciding the mathematical model, teacher should consider students’ characteristic, the material, and also the students’ habits. So far, mathematics
Evi , Suharyanti +3 more
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Wanted: Trained Security Specialists\u27
, 2008 This paper looks at security concerns within the IT industry and how to increase student interest in this field of study. One specific activity is presented as a way to expose students to security concerns they are likely to encounter as a system ...
Wilson, Brent +2 more
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
What Are They Doing Anyway?: Library as Place and Student Use of a University Library
Evidence Based Library and Information Practice, 2017 Objective - To determine student use of library spaces, the authors recorded student location and behaviors within the Library, to inform future space design.
Angelica Ferria +6 more
doaj
PEMAHAMAN SISWA PADA SUB POKOK PEMBAHASAN BANGUN DATAR SEGI-4 DENGAN PEMBELAJARAN KOOPERATIF MODEL (GI) GROUP INVESTIGATION KELAS VII SMP ISLAM NURURIYADLAH PAITON PROBOLINGGO [PDF]
, 2009 See still to the number of applying of study having the character of conventional hence require to perform of renewal to increase the quality of study process , specially study of mathematics.
Rohman, Hasbullah
core