Results 231 to 240 of about 70,487 (294)

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman   +6 more
wiley   +1 more source

Understanding the influence of transfusion and blood loss on tranexamic acid concentration in scoliosis surgery with blood loss

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Tranexamic acid (TXA) stabilizes clot formation by inhibiting fibrin degradation and improves postoperative outcomes. However, rare adverse events (e.g., thrombosis, seizures) warrant dose–risk evaluation. This study examines how perioperative blood loss and transfusion practices affect TXA concentrations during paediatric scoliosis surgery ...
Paula Alexandra Sá   +4 more
wiley   +1 more source

Potential of a digital parenting app to support parents of toddlers: Relations between the intensity of app use, language‐related parental self‐efficacy and the home literacy environment

open access: yesBritish Educational Research Journal, EarlyView.
Abstract The home literacy environment (HLE) has a considerable influence on children's language development. How parents perceive their own parenting abilities (e.g., how well they encourage their children's language development) is particularly important when it comes to guiding their children appropriately through different stages of development ...
Luisa Prokupek   +4 more
wiley   +1 more source

Retention among newly qualified second‐year teachers: The reception–integration model

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Drawing on organisational socialisation theory, the study seeks to explore the mechanisms that foster retention among second‐year teachers. This examination considered these novice teachers' experiences during their first year of teaching, with a particular emphasis on the reception they encountered as they entered the teaching profession, as ...
Rinat Arviv Elyashiv   +2 more
wiley   +1 more source

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