Results 61 to 70 of about 281,783 (266)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Understanding library impacts on student learning

open access: yesIn the Library with the Lead Pipe, 2011
In the Library with the Lead Pipe is pleased to welcome guest author Derek Rodriguez. Derek serves as a Program Officer with the Triangle Research Libraries Network where he supports collaborative technology initiatives within the consortium and is ...
Derek Rodriguez
doaj  

Assessing Public Health Majors through the Use of e-Portfolios

open access: yesJournal of the Scholarship of Teaching and Learning, 2016
When assessing an entire academic program, there are various possibilities; most require students to reflect holistically on knowledge learned. Final presentations, internships, theses, and dissertations all require the students to recall the entirety of
Tara L. Crowell, Elizabeth Calamidas
doaj   +1 more source

Teacher Classroom Questioning Practice and Assessment Literacy: Case Studies of Four English Language Teachers in Chinese Universities

open access: yesFrontiers in Education, 2020
This study examined classroom teacher questioning practice and explored how this process was affected by teacher assessment literacy and other mediating factors based on four case studies.
Yan Jiang
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Architectural Competitions: An Innovative Tool for Developing Architecture Education and Professional Practice [PDF]

open access: yesFayoum University Journal of Engineering
Architectural competition is one of the important paths in the process of architecture education and professional practice. It is considered as a kind of collaborative learning and one of the crucial educational methods that adopt the development of ...
Riham Faragallah
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Student Involvement for Student Success: Student Staff in the Learning Commons

open access: yesCollege & Research Libraries, 2014
How do you effectively train and assess student staff in a learning commons environment? How do you foster a student-led approach while maintaining accurate and high-level service? How do you create an environment where student staff are engaged and motivated to succeed?
Julie Mitchell, Nathalie Soini
openaire   +2 more sources

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