Fine-grained causal effect estimation of learning resources via dynamic causal heterogeneous graph neural networks. [PDF]
Sci RepRen Y, Chen Z, Jiang X, Du Z.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Associations between perceived teacher-student interaction quality and intrinsic motivation and psychological resilience in one-on-one clarinet instruction: a social cognitive theory perspective. [PDF]
BMC PsycholSun J.
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
A study on the application of multimodal technologies in personalized training systems for the integration of physical education and general education. [PDF]
BMC Sports Sci Med RehabilLin H, Guo Z.
europepmc +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Whole slide imaging in medical education: A comparative study of learning experience and engagement using cognitive diagnostic modeling. [PDF]
Acad PatholKhacheishvili M +2 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Protocol for development of an AI-driven individualized frailty prediction and intervention framework for elderly patients with chronic kidney disease: causal feature learning and knowledge-distillation-based modeling study. [PDF]
BMC GeriatrChang J +11 more
europepmc +1 more source