Results 141 to 150 of about 6,137,161 (322)

An Examination of Student Performance in Pre-Requisite Coursework and Upper Division Nursing Coursework [PDF]

open access: yes, 2019
Admission and retention of qualified nursing students are essential in meeting the demands of a rapidly changing health care environment and nursing shortage.
Brown, Jennifer L, Smith, Cheryl M
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Do students in UK Higher Education Institutions need personal tutors? [PDF]

open access: yes, 2011
This paper critically analyses the role of Personal Tutoring (PT) as a mechanism for providing student support in Higher Education (HE) in the UK. The discussions presented will draw on the experiences of PT at City University, London (City), as well as ...
Lindsay, S.
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Instructor Maladaptive and Adaptive Relational Styles (I-MARS) as drivers of online-student retention and satisfaction

open access: yesComputers and Education Open
This study retrospectively assessed forum and module-based email communications between instructors and students. The data set analysed consisted of 40.000 forum posts and 10.000 Blackboard emails matched with 522 end of module student surveys extracted ...
Stamatis Elntib
doaj   +1 more source

From despair to somewhere: activating students in a distance learning environment [PDF]

open access: yes, 2015
Student engagement in part-time and distance learning is critical in terms of retention and progression. But ideas about engagement often focus on academic priorities and on students who collude with the concept of being “active” learners. To establish a
Foley, Karen   +2 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Improving student retention and success: Realising the (im)possible

open access: yesWest African Journal of Open and Flexible Learning, 2022
Paul Prinsloo
doaj  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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