Results 121 to 130 of about 107,928 (308)

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Towards the development of a prognostic approach to Student retention in foreign language classes

, 2011
Language student attrition rightly continues to raise concern, associated as it is with heavy emotional and financial consequences. Existing models of student retention and attrition approach the issue of student dropout once the students had withdrawn ...
Lobo, A, Matas, CP
core  

International student complaint behaviour: Understanding how East-Asian business and management students respond to dissatisfaction during their university experience

, 2011
The higher education sector is characterised by intense global competition for international students. This is driving universities to place greater priority on the student experience and, in particular, student satisfaction and retention.
Coates, Nigel, Hart, David, David Hart, Nigel Coates   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A correlation analysis of the Noel-Levitz Instrument and student program retention data at Chippewa Valley Technical College [PDF]

, 2006
Includes bibliographical ...
Keys, Margo
core  

Improving student retention and success: Realising the (im)possible

West African Journal of Open and Flexible Learning, 2022
Paul Prinsloo
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Grade retention and educational attainment. Exploiting the 2001 Reform by the French-Speaking Community of Belgium and Synthetic Control Methods [PDF]

This paper evaluates the effects of grade retention on attainment by exploiting a reform introduced in 2001 in the French-Speaking Community of Belgium whereby the possibility of grade retention in grade 7 was reintroduced.
Michele BELOT, Vincent VANDENBERGHE
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Longitudinal Impact of Grade Retention on Student Engagement with School: Challenges to Inclusive Education and to Person-Centered Schools

European Journal of Investigation in Health, Psychology and Education
The value of grade retention as a pedagogic resource remains a subject of debate because of its costs and benefits. In fact, it has been repeatedly argued that grade retention has substantial psychosocial effects. Student engagement with school is one of
Alberta Sousa, Maria João Rodrigues, Mariana Rodrigues, Nadine Poltz, Angeles Conde-Rodriguez, Paulo A. S. Moreira   +5 more
doaj   +1 more source